Difference between revisions of "L-box"
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− | The L-box is a [[riboswitch]] that binds lysine and controls gene expression by a termination/ antitermination mechanism. | + | The L-box is a [[riboswitch]] that binds lysine and controls gene expression by a termination/ antitermination mechanism. Upon binding of lysine, the L-box adopts a terminator structure thtus preventing expression of ''[[lysC]]''. In the absence of lysine, the L-box has an antiterminator structure that allows ''[[lysC]]'' expression and thus lysine biosynthesis. |
==Gene controlled by a L-box mechanism== | ==Gene controlled by a L-box mechanism== | ||
Line 5: | Line 5: | ||
[[lysC]] | [[lysC]] | ||
+ | ==Reference== | ||
<pubmed> 14523230 </pubmed> | <pubmed> 14523230 </pubmed> |
Revision as of 13:00, 7 June 2009
The L-box is a riboswitch that binds lysine and controls gene expression by a termination/ antitermination mechanism. Upon binding of lysine, the L-box adopts a terminator structure thtus preventing expression of lysC. In the absence of lysine, the L-box has an antiterminator structure that allows lysC expression and thus lysine biosynthesis.
Gene controlled by a L-box mechanism
Reference
Frank J Grundy, Susan C Lehman, Tina M Henkin
The L box regulon: lysine sensing by leader RNAs of bacterial lysine biosynthesis genes.
Proc Natl Acad Sci U S A: 2003, 100(21);12057-62
[PubMed:14523230]
[WorldCat.org]
[DOI]
(P p)