Difference between revisions of "FolD"
| Line 35: | Line 35: | ||
=== Basic information === | === Basic information === | ||
| − | * '''Locus tag:''' | + | * '''Locus tag:''' BSU24310 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| Line 82: | Line 82: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P54382 P54382] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P54382 P54382] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU24310] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.5.1.5 1.5.1.5] | * '''E.C. number:''' [http://www.expasy.org/enzyme/1.5.1.5 1.5.1.5] | ||
Revision as of 09:29, 3 June 2009
- Description: methylenetetrahydrofolate dehydrogenase (NADP)
| Gene name | folD |
| Synonyms | yqiA |
| Essential | yes PubMed |
| Product | methylenetetrahydrofolate dehydrogenase (NADP) |
| Function | formylation of Met-tRNA(fMet) |
| MW, pI | 30 kDa, 5.6 |
| Gene length, protein length | 849 bp, 283 aa |
| Immediate neighbours | yqiB, nusB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU24310
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH (according to Swiss-Prot)
- Protein family: tetrahydrofolate dehydrogenase/cyclohydrolase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P54382
- KEGG entry: [3]
- E.C. number: 1.5.1.5
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Yann Duroc, Carmela Giglione, Thierry Meinnel
Mutations in three distinct loci cause resistance to peptide deformylase inhibitors in Bacillus subtilis.
Antimicrob Agents Chemother: 2009, 53(4);1673-8
[PubMed:19171795]
[WorldCat.org]
[DOI]
(I p)
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
