Difference between revisions of "Sandbox"

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* '''Description:''' 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase <br/><br/>
+
* '''Description:''' penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yngG''
+
|''dacC''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''pbp ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase
+
|style="background:#ABCDEF;" align="center"| '''Product''' || penicillin-binding protein 4A, <br/>D-alanyl-D-alanine carboxypeptidase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of ketone bodies
+
|style="background:#ABCDEF;" align="center"|'''Function''' || carboxypeptidase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 5.753  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 52 kDa, 5.413  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 897 bp, 299 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1473 bp, 491 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yngF]]'', ''[[yngH]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ppsA]]'', ''[[yoxA]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13706&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13718&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|-
 
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:yngG_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:dacC_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
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__TOC__
 
__TOC__
  
<br/><br/>
+
<br/><br/><br/>
  
 
=The gene=
 
=The gene=
Line 41: Line 41:
 
=== Database entries ===
 
=== Database entries ===
  
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yngJIHGFE.html]
+
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yoxA-dacC.html]
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13458]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10969]
  
 
=== Additional information===
 
=== Additional information===
Line 76: Line 76:
 
=== Database entries ===
 
=== Database entries ===
  
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1YDO 1YDO]
+
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2J9P 2J9P] (complex with a peptidoglycan mimetic peptide)
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O34873 O34873]
+
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39844 P39844]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU18230]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU18350]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''

Revision as of 15:40, 5 May 2009

  • Description: penicillin-binding protein 4A, D-alanyl-D-alanine carboxypeptidase

Gene name dacC
Synonyms pbp
Essential no
Product penicillin-binding protein 4A,
D-alanyl-D-alanine carboxypeptidase
Function carboxypeptidase
MW, pI 52 kDa, 5.413
Gene length, protein length 1473 bp, 491 aa
Immediate neighbours ppsA, yoxA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DacC context.gif
This image was kindly provided by SubtiList




The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 2J9P (complex with a peptidoglycan mimetic peptide)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed