Difference between revisions of "Sandbox"

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* '''Description:''' protein serine phosphatase, septum-associated PP2C, dephosphorylation of [[SpoIIAA]] <br/><br/>
+
* '''Description:''' para-aminobenzoate synthase (subunit A) <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''spoIIE''
+
|''pabB''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''spoIIH, spoIIK ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''pab ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || protein serine phosphatase, septum-associated PP2C
+
|style="background:#ABCDEF;" align="center"| '''Product''' || para-aminobenzoate synthase (subunit A)
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigF]] activity
+
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of folate
required for normal formation of the asymmetric septum
 
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 91 kDa, 6.137  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 5.234  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2481 bp, 827 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1410 bp, 470 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[trnSL-Glu1]]'', ''[[yabS]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cysK]]'', ''[[pabA]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11840&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11850&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|-
 
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:spoIIE_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:pabB_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
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=== Database entries ===
 
=== Database entries ===
  
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIIE.html]
+
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pabBAC-sul-folBK-yazB-yacF-lysS.html]
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10127]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10137]
  
 
=== Additional information===
 
=== Additional information===
Line 53: Line 52:
 
=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' dephosphorylation of [[SpoIIAA]]
+
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:''' PP2C phosphatase
+
* '''Protein family:'''
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
Line 71: Line 70:
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:''' [[SpoIIE]]-[[FtsZ]]
+
* '''Interactions:''' [[PabA]]-[[PabB]],  [[PabA]]-[[PabB]]  
  
 
* '''Localization:'''
 
* '''Localization:'''
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* '''Swiss prot entry:'''
 
* '''Swiss prot entry:'''
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU00640]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU00740]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''
Line 114: Line 113:
  
 
=Labs working on this gene/protein=
 
=Labs working on this gene/protein=
 
[[Imrich Barak]], Slovak Academy of Science, Bratislava, Slovakia [http://imb.savba.sk/~barak/ homepage]
 
  
 
=Your additional remarks=
 
=Your additional remarks=

Revision as of 13:43, 28 April 2009

  • Description: para-aminobenzoate synthase (subunit A)

Gene name pabB
Synonyms pab
Essential no
Product para-aminobenzoate synthase (subunit A)
Function biosynthesis of folate
MW, pI 53 kDa, 5.234
Gene length, protein length 1410 bp, 470 aa
Immediate neighbours cysK, pabA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PabB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed