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| − | * '''Description:''' seryl-tRNA-synthetase <br/><br/>
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| − | {| align="right" border="1" cellpadding="2"
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| − | |-
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| − | |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| − | |''serS''
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| − | |-
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| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| − | |-
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| − | |style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
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| − | |-
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || seryl-tRNA-synthetase
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| − | |-
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || translation
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| − | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 48 kDa, 5.193
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| − | |-
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| − | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1275 bp, 425 aa
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| − | |-
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| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pdxT]]'', ''[[trnSL-Ser1]]''
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| − | |-
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| − | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB11789]+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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| − | |-
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| − | |colspan="2" | '''Genetic context''' <br/> [[Image:serS_context.gif]]
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| − | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| − | |-
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| − | |}
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| − | __TOC__
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| − | <br/><br/>
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| − |
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| − | =The gene=
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| − |
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| − | === Basic information ===
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| − | * '''Coordinates:'''
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| − |
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| − | ===Phenotypes of a mutant ===
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| − | essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
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| − |
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| − | === Database entries ===
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| − | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/serS.html]
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| − | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10077]
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| − |
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| − | === Additional information===
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| − |
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| − |
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| − | =The protein=
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| − |
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| − | === Basic information/ Evolution ===
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| − | * '''Catalyzed reaction/ biological activity:'''
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| − | * '''Protein family:'''
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| − |
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| − | * '''Paralogous protein(s):'''
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| − |
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| − | === Extended information on the protein ===
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| − | * '''Kinetic information:'''
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| − | * '''Domains:'''
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| − | * '''Modification:'''
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| − | * '''Cofactor(s):'''
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| − | * '''Effectors of protein activity:'''
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| − | * '''Interactions:'''
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| − | * '''Localization:''' Cytoplasm
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| − |
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| − | === Database entries ===
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| − | * '''Structure:'''
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| − | * '''Swiss prot entry:'''
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| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU00130]
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| − | * '''E.C. number:'''
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| − |
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| − | === Additional information===
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| − | =Expression and regulation=
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| − | * '''Operon:''' ''serS'' [http://www.ncbi.nlm.nih.gov/sites/entrez/8915527 PubMed]
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| − | * '''[[Sigma factor]]:'''
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| − | * '''Regulation:''' induced in the presence of serine [http://www.ncbi.nlm.nih.gov/sites/entrez/8915527 PubMed]
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| − | * '''Regulatory mechanism:''' antitermination by a ''[[trnD-Ser]]-''dependent RNA switch [http://www.ncbi.nlm.nih.gov/sites/entrez/8915527 PubMed]
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| − | * '''Additional information:'''
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| − |
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| − | =Biological materials =
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| − |
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| − | * '''Mutant:'''
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| − | * '''Expression vector:'''
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| − |
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| − | * '''lacZ fusion:'''
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| − | * '''GFP fusion:'''
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| − | * '''two-hybrid system:'''
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| − | * '''Antibody:'''
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| − | =Labs working on this gene/protein=
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| − | =Your additional remarks=
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| − | =References=
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| − | # Condon et al. (1996) Aminoacyl-tRNA synthetase gene regulation in ''Bacillus subtilis''.
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| − | ''Biochimie'' '''78:''' 381-389. [http://www.ncbi.nlm.nih.gov/sites/entrez/8915527 PubMed]
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