Difference between revisions of "Sandbox"

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* '''Description:''' holin, required for spore morphogenesis and germination <br/><br/>
+
* '''Description:''' control of cell shape and elongation <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ywcE''
+
|''rodA''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ipa-41r ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ywcF, ipa-42d ''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
+
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || holin
+
|style="background:#ABCDEF;" align="center"| '''Product''' || SEDS protein
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || required for spore morphogenesis and germination
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of cell shape and elongation
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 9.845  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 8.759  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 261 bp, 87 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1179 bp, 393 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rodA]]'', ''[[qoxD]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nfrA]]'', ''[[ywcE]]''
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein'''
 
|-
 
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:ywcE_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:rodA_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
Line 38: Line 38:
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
 +
essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
  
 
=== Database entries ===
 
=== Database entries ===
  
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ywcE.html]
+
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/rodA.html]
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10587]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10588]
  
 
=== Additional information===
 
=== Additional information===
Line 54: Line 56:
 
* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:'''
+
* '''Protein family:''' SEDS proteins (shape, elongation, division, and sporulation)
  
* '''Paralogous protein(s):'''
+
* '''Paralogous protein(s):''' [[FtsW]], [[SpoVE]]
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
Line 80: Line 82:
 
* '''Swiss prot entry:'''
 
* '''Swiss prot entry:'''
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU38130]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU38120]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''
Line 90: Line 92:
 
* '''Operon:'''  
 
* '''Operon:'''  
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigM]] [http://www.ncbi.nlm.nih.gov/sites/entrez/18179421 Pubmed]
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
Line 96: Line 98:
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
  
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =
Line 118: Line 120:
 
=References=
 
=References=
  
 +
# Henriques AO, Glaser P, Piggot PJ, Moran CP Jr. (1998) Control of cell shape and elongation by the rodA gene in Bacillus subtilis. ''Mol Microbiol.'' '''Apr;28(2):''' 235-47. [http://www.ncbi.nlm.nih.gov/sites/entrez/9622350 PubMed]
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
 
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]

Revision as of 17:07, 15 April 2009

  • Description: control of cell shape and elongation

Gene name rodA
Synonyms ywcF, ipa-42d
Essential yes PubMed
Product SEDS protein
Function control of cell shape and elongation
MW, pI 43 kDa, 8.759
Gene length, protein length 1179 bp, 393 aa
Immediate neighbours nfrA, ywcE
Hier soll was neues rein
Genetic context
RodA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: SEDS proteins (shape, elongation, division, and sporulation)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Henriques AO, Glaser P, Piggot PJ, Moran CP Jr. (1998) Control of cell shape and elongation by the rodA gene in Bacillus subtilis. Mol Microbiol. Apr;28(2): 235-47. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed