Difference between revisions of "Sandbox"

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* '''Description:''' dihydropteroate synthase <br/><br/>
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* '''Description:''' 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
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|''sul''
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|''folK''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Product''' || dihydropteroate synthase
+
|style="background:#ABCDEF;" align="center"| '''Product''' || 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of folate  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of folate  
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 30 kDa, 5.363  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 4.531  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 855 bp, 285 aa  
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 501 bp, 167 aa  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pabC]]'', ''[[folB]]''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[folB]]'', ''[[yazB]]''
 
|-
 
|-
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/sul_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/folK_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/sul_protein.txt Protein sequence]'''
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/folK_protein.txt Protein sequence]'''
 
|-
 
|-
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|colspan="2" | '''Genetic context''' <br/> [[Image:sul_context.gif]]
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|colspan="2" | '''Genetic context''' <br/> [[Image:folK_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
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* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pabBAC-sul-folBK-yazB-yacF-lysS.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pabBAC-sul-folBK-yazB-yacF-lysS.html]
  
−
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10140]
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* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10142]
  
 
=== Additional information===
 
=== Additional information===
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
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* '''Protein family:''' pterin-binding domain
+
* '''Protein family:''' HPPK family
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
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* '''Swiss prot entry:'''
 
* '''Swiss prot entry:'''
  
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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU00770]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU00790]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''

Revision as of 02:55, 12 April 2009

  • Description: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase

Gene name folK
Synonyms
Essential no
Product 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
Function biosynthesis of folate
MW, pI 18 kDa, 4.531
Gene length, protein length 501 bp, 167 aa
Immediate neighbours folB, yazB
Gene sequence (+200bp) Protein sequence
Genetic context
FolK context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: HPPK family
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
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