Difference between revisions of "Sandbox"

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* '''Description:''' glycine decarboxylase (subunit 1) <br/><br/>
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* '''Description:''' glycine decarboxylase (subunit 2) <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
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|''gcvPA''
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|''gcvPB''
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yqhJ, gcvP ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yqhK, gcvP ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Product''' || glycine decarboxylase (subunit 1)
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|style="background:#ABCDEF;" align="center"| '''Product''' || glycine decarboxylase (subunit 2)
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || glycine utilization  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || glycine utilization  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 49 kDa, 6.947  
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 54 kDa, 5.283  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1344 bp, 448 aa  
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1464 bp, 488 aa  
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gcvPB]]'', ''[[gcvT]]''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqhL]]'', ''[[gcvPA]]''
 
|-
 
|-
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/gcvPA_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/gcvPB_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/gcvPA_protein.txt Protein sequence]'''
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/gcvPB_protein.txt Protein sequence]'''
 
|-
 
|-
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|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | '''Caution: The sequence for this gene in SubtiList contains errors
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|colspan="2" | '''Genetic context''' <br/> [[Image:gcvPB_context.gif]]
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|-
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:gcvPA_context.gif]]
 
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
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* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gcvT-gcvPA-gcvPB.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gcvT-gcvPA-gcvPB.html]
  
−
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11510]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11511]
  
 
=== Additional information===
 
=== Additional information===
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* '''Swiss prot entry:'''
 
* '''Swiss prot entry:'''
  
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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU24560]
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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU24550]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''

Revision as of 11:13, 31 March 2009

  • Description: glycine decarboxylase (subunit 2)

Gene name gcvPB
Synonyms yqhK, gcvP
Essential no
Product glycine decarboxylase (subunit 2)
Function glycine utilization
MW, pI 54 kDa, 5.283
Gene length, protein length 1464 bp, 488 aa
Immediate neighbours yqhL, gcvPA
Gene sequence (+200bp) Protein sequence
Genetic context
GcvPB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: repressed by Casamino Acids PubMed , induced by glycine PubMed
  • Regulatory mechanism: induction requires a co-operatively acting riboswitch PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Mäder et al. (2002) Transcriptome and Proteome Analysis of Bacillus subtilis Gene Expression Modulated by Amino Acid Availability. J. Bacteriol 184: 1844288-4295 PubMed
  2. Mandal M, Lee M, Barrick JE, Weinberg Z, Emilsson GM, Ruzzo WL, Breaker RR (2004) A glycine-dependent riboswitch that uses cooperative binding to control gene expression. Science 306: 275-279. PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
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