Difference between revisions of "Stusti 2018"

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==  What makes RNA such a special molecule – specific chemical and structural features of RNA ==
 
==  What makes RNA such a special molecule – specific chemical and structural features of RNA ==
<pubmed>  21930584
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<pubmed>  21930584</pubmed>
</pubmed>
 
  
 
== RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair ==
 
== RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair ==
<pubmed>  24219496 8156586 28979293     26109351
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<pubmed>  24219496 8156586 28979293 26109351</pubmed>
</pubmed>
 
  
== Ribozymes (catalytically active RNAs)(Intro)==
+
== Ribozymes (catalytically active RNAs) (Intro)==
<pubmed>     21930582  
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<pubmed> 21930582</pubmed>
</pubmed>
 
  
== The Ribosome - the role and function of ribosomal RNAs     and the central dogma of molecular biology ==
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== The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology ==
<pubmed>     18292779 21930591 25500179
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<pubmed> 18292779 21930591 25500179</pubmed>
</pubmed>
 
  
 
== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ==
 
== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity ==
<pubmed> 24452469 26682498 25798239
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<pubmed> 24452469,26682498 25798239 </pubmed>
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== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme & Co ==
 
== Protein independent ribozymes – about Hammerhead,  Varkud satellite,  hairpin ribozyme & Co ==
<pubmed> 22454536,14730013 10554775 21930585 6297745</pubmed>
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<pubmed> 22454536 14730013 10554775 21930585 6297745</pubmed>
  
 
== RNA-based second messengers ==
 
== RNA-based second messengers ==
<pubmed>28420751    25616065 25682701    25869574 26280533</pubmed>
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<pubmed> 28420751    25616065 25682701    25869574 26280533</pubmed>
  
 
== Riboregulation and virulence, targeting by antibiotics ==
 
== Riboregulation and virulence, targeting by antibiotics ==
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== Protein- or tRNA-controlled RNA switches ==
 
== Protein- or tRNA-controlled RNA switches ==
<pubmed>25959893        24816551
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25583497</pubmed>
 
  
 
== RNA thermometers ==
 
== RNA thermometers ==
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== RNA dependent DNA Polymerases - from telomerase to retroviruses==
 
== RNA dependent DNA Polymerases - from telomerase to retroviruses==
<pubmed>      18972389 26830230     28141967
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<pubmed>      18972389 26830230     28141967 </pubmed>  
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== RNA dependent RNA Polymerases – the RNA replicase ==
 
== RNA dependent RNA Polymerases – the RNA replicase ==
<pubmed>          29439438     18268843 9878607
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<pubmed>          29439438     18268843 9878607 </pubmed>  
</pubmed>  
 
  
 
== CRISPR/Cas: Science – the bacterial “immune” system ==
 
== CRISPR/Cas: Science – the bacterial “immune” system ==
<pubmed>      29358495      29169146
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<pubmed>      29358495      29169146 28375731</pubmed>
    28375731</pubmed>
 
  
 
== CRISPR/Cas: Application and groundbreaking  perspectives ==
 
== CRISPR/Cas: Application and groundbreaking  perspectives ==
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== The mysterious function and role of 6S-RNA and pRNA in bacteria ==
 
== The mysterious function and role of 6S-RNA and pRNA in bacteria ==
<pubmed>    24786589 17383220 24742053 23457253
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<pubmed>    24786589 17383220 24742053 23457253</pubmed>  
</pubmed>  
 
  
 
== Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer ==
 
== Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer ==
<pubmed>     22016848 26186290     21957054 23166520 21930591
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<pubmed>   22016848 26186290 21957054 23166520 21930591</pubmed>  
</pubmed>  
 
  
 
== Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA) ==
 
== Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA) ==
<pubmed>         28533025 25561718 26883671
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<pubmed>       28533025 25561718 26883671 28485684 29182528 21925379</pubmed>
    28485684 29182528 21925379
 
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== Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways ==
 
== Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways ==
<pubmed>   17627883     19943183   
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<pubmed> 17627883 19943183  </pubmed>
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Revision as of 13:37, 22 June 2018

Contents

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

What makes RNA such a special molecule – specific chemical and structural features of RNA


RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair


Ribozymes (catalytically active RNAs) (Intro)


The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology


The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity


Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co


RNA-based second messengers


Riboregulation and virulence, targeting by antibiotics

Juan J Quereda, Pascale Cossart
Regulating Bacterial Virulence with RNA.
Annu Rev Microbiol: 2017, 71;263-280
[PubMed:28886688] [WorldCat.org] [DOI] (I p)

Petra Dersch, Muna A Khan, Sabrina Mühlen, Boris Görke
Roles of Regulatory RNAs for Antibiotic Resistance in Bacteria and Their Potential Value as Novel Drug Targets.
Front Microbiol: 2017, 8;803
[PubMed:28529506] [WorldCat.org] [DOI] (P e)

Hao Wang, Paul A Mann, Li Xiao, Charles Gill, Andrew M Galgoci, John A Howe, Artjohn Villafania, Christopher M Barbieri, Juliana C Malinverni, Xinwei Sher, Todd Mayhood, Megan D McCurry, Nicholas Murgolo, Amy Flattery, Matthias Mack, Terry Roemer
Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.
Cell Chem Biol: 2017, 24(5);576-588.e6
[PubMed:28434876] [WorldCat.org] [DOI] (I p)

Andreas Matern, Danielle Pedrolli, Stephanie Großhennig, Jörgen Johansson, Matthias Mack
Uptake and Metabolism of Antibiotics Roseoflavin and 8-Demethyl-8-Aminoriboflavin in Riboflavin-Auxotrophic Listeria monocytogenes.
J Bacteriol: 2016, 198(23);3233-3243
[PubMed:27672192] [WorldCat.org] [DOI] (I e)

Aaron M Nuss, Ann Kathrin Heroven, Petra Dersch
RNA Regulators: Formidable Modulators of Yersinia Virulence.
Trends Microbiol: 2017, 25(1);19-34
[PubMed:27651123] [WorldCat.org] [DOI] (I p)

Daniel Dar, Maya Shamir, J R Mellin, Mikael Koutero, Noam Stern-Ginossar, Pascale Cossart, Rotem Sorek
Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria.
Science: 2016, 352(6282);aad9822
[PubMed:27120414] [WorldCat.org] [DOI] (I p)

John A Howe, Hao Wang, Thierry O Fischmann, Carl J Balibar, Li Xiao, Andrew M Galgoci, Juliana C Malinverni, Todd Mayhood, Artjohn Villafania, Ali Nahvi, Nicholas Murgolo, Christopher M Barbieri, Paul A Mann, Donna Carr, Ellen Xia, Paul Zuck, Dan Riley, Ronald E Painter, Scott S Walker, Brad Sherborne, Reynalda de Jesus, Weidong Pan, Michael A Plotkin, Jin Wu, Diane Rindgen, John Cummings, Charles G Garlisi, Rumin Zhang, Payal R Sheth, Charles J Gill, Haifeng Tang, Terry Roemer
Selective small-molecule inhibition of an RNA structural element.
Nature: 2015, 526(7575);672-7
[PubMed:26416753] [WorldCat.org] [DOI] (I p)


Riboswitches


Protein- or tRNA-controlled RNA switches


RNA thermometers


The RNA world and evolution


RNA modification

Baixing Wu, Li Li, Ying Huang, Jinbiao Ma, Jinrong Min
##Title##
Curr Opin Struct Biol: 2017, 47;67-76
[PubMed:28624569] [WorldCat.org] [DOI] (I p)

Hiroyuki Hori
Transfer RNA methyltransferases with a SpoU-TrmD  (SPOUT) fold and their modified nucleosides in  tRNA.
Biomolecules: 2017, 7(1);
[PubMed:28264529] [WorldCat.org] [DOI] (I e)

Ajay K Rana, Serge Ankri
Reviving the RNA World: An Insight into the Appearance of RNA Methyltransferases.
Front Genet: 2016, 7;99
[PubMed:27375676] [WorldCat.org] [DOI] (P e)

Marcus Fislage, Lina Wauters, Wim Versées
Invited review: MnmE, a GTPase that drives a complex tRNA modification reaction.
Biopolymers: 2016, 105(8);568-79
[PubMed:26832457] [WorldCat.org] [DOI] (I p)

Clément Dégut, Luc Ponchon, Marcia Folly-Klan, Pierre Barraud, Carine Tisné
The m1A(58) modification in eubacterial tRNA: An overview of tRNA recognition and mechanism of catalysis by TrmI.
Biophys Chem: 2016, 210;27-34
[PubMed:26189113] [WorldCat.org] [DOI] (I p)


RNA degradation/processing

John C Zinder, Christopher D Lima
Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors.
Genes Dev: 2017, 31(2);88-100
[PubMed:28202538] [WorldCat.org] [DOI] (I p)

Soraya Aït-Bara, Agamemnon J Carpousis
RNA degradosomes in bacteria and chloroplasts: classification, distribution and evolution of RNase E homologs.
Mol Microbiol: 2015, 97(6);1021-135
[PubMed:26096689] [WorldCat.org] [DOI] (I p)

Jonathan Houseley, David Tollervey
The many pathways of RNA degradation.
Cell: 2009, 136(4);763-76
[PubMed:19239894] [WorldCat.org] [DOI] (I p)


Regulation by non-coding RNA



RNA dependent DNA Polymerases - from telomerase to retroviruses


RNA dependent RNA Polymerases – the RNA replicase


CRISPR/Cas: Science – the bacterial “immune” system


CRISPR/Cas: Application and groundbreaking perspectives


The mysterious function and role of 6S-RNA and pRNA in bacteria


Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer


Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)


Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways