Difference between revisions of "Stusti 2018"
| Line 2: | Line 2: | ||
== What makes RNA such a special molecule – specific chemical and structural features of RNA == | == What makes RNA such a special molecule – specific chemical and structural features of RNA == | ||
| − | <pubmed> 21930584 | + | <pubmed> 21930584</pubmed> |
| − | </pubmed> | ||
== RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair == | == RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair == | ||
| − | <pubmed> 24219496 | + | <pubmed> 24219496 8156586 28979293 26109351</pubmed> |
| − | </pubmed> | ||
| − | == Ribozymes (catalytically active RNAs)(Intro)== | + | == Ribozymes (catalytically active RNAs) (Intro)== |
| − | <pubmed> | + | <pubmed> 21930582</pubmed> |
| − | </pubmed> | ||
| − | == The Ribosome - the role and function of ribosomal RNAs | + | == The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology == |
| − | <pubmed> | + | <pubmed> 18292779 21930591 25500179</pubmed> |
| − | </pubmed> | ||
== The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity == | == The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity == | ||
| − | <pubmed> | + | <pubmed> 24452469,26682498 25798239 </pubmed> |
| − | </pubmed> | ||
== Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co == | == Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co == | ||
| − | <pubmed> | + | <pubmed> 22454536 14730013 10554775 21930585 6297745</pubmed> |
== RNA-based second messengers == | == RNA-based second messengers == | ||
| − | <pubmed>28420751 25616065 25682701 25869574 26280533</pubmed> | + | <pubmed> 28420751 25616065 25682701 25869574 26280533</pubmed> |
== Riboregulation and virulence, targeting by antibiotics == | == Riboregulation and virulence, targeting by antibiotics == | ||
| Line 35: | Line 30: | ||
== Protein- or tRNA-controlled RNA switches == | == Protein- or tRNA-controlled RNA switches == | ||
| − | <pubmed>25959893 24816551 | + | <pubmed>25959893 24816551 25583497</pubmed> |
| − | |||
== RNA thermometers == | == RNA thermometers == | ||
| Line 55: | Line 49: | ||
== RNA dependent DNA Polymerases - from telomerase to retroviruses== | == RNA dependent DNA Polymerases - from telomerase to retroviruses== | ||
| − | <pubmed> 18972389 26830230 28141967 | + | <pubmed> 18972389 26830230 28141967 </pubmed> |
| − | </pubmed> | ||
== RNA dependent RNA Polymerases – the RNA replicase == | == RNA dependent RNA Polymerases – the RNA replicase == | ||
| − | <pubmed> 29439438 18268843 9878607 | + | <pubmed> 29439438 18268843 9878607 </pubmed> |
| − | </pubmed> | ||
== CRISPR/Cas: Science – the bacterial “immune” system == | == CRISPR/Cas: Science – the bacterial “immune” system == | ||
| − | <pubmed> 29358495 29169146 | + | <pubmed> 29358495 29169146 28375731</pubmed> |
| − | |||
== CRISPR/Cas: Application and groundbreaking perspectives == | == CRISPR/Cas: Application and groundbreaking perspectives == | ||
| Line 70: | Line 61: | ||
== The mysterious function and role of 6S-RNA and pRNA in bacteria == | == The mysterious function and role of 6S-RNA and pRNA in bacteria == | ||
| − | <pubmed> 24786589 | + | <pubmed> 24786589 17383220 24742053 23457253</pubmed> |
| − | </pubmed> | ||
== Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer == | == Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer == | ||
| − | <pubmed> | + | <pubmed> 22016848 26186290 21957054 23166520 21930591</pubmed> |
| − | </pubmed> | ||
== Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA) == | == Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA) == | ||
| − | <pubmed> | + | <pubmed> 28533025 25561718 26883671 28485684 29182528 21925379</pubmed> |
| − | |||
| − | </pubmed> | ||
== Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways == | == Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways == | ||
| − | <pubmed> | + | <pubmed> 17627883 19943183 </pubmed> |
| − | </pubmed> | ||
Revision as of 13:37, 22 June 2018
Contents
- 1 Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas
- 1.1 What makes RNA such a special molecule – specific chemical and structural features of RNA
- 1.2 RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair
- 1.3 Ribozymes (catalytically active RNAs) (Intro)
- 1.4 The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology
- 1.5 The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity
- 1.6 Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co
- 1.7 RNA-based second messengers
- 1.8 Riboregulation and virulence, targeting by antibiotics
- 1.9 Riboswitches
- 1.10 Protein- or tRNA-controlled RNA switches
- 1.11 RNA thermometers
- 1.12 The RNA world and evolution
- 1.13 RNA modification
- 1.14 RNA degradation/processing
- 1.15 Regulation by non-coding RNA
- 1.16 RNA dependent DNA Polymerases - from telomerase to retroviruses
- 1.17 RNA dependent RNA Polymerases – the RNA replicase
- 1.18 CRISPR/Cas: Science – the bacterial “immune” system
- 1.19 CRISPR/Cas: Application and groundbreaking perspectives
- 1.20 The mysterious function and role of 6S-RNA and pRNA in bacteria
- 1.21 Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer
- 1.22 Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)
- 1.23 Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways
Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas
What makes RNA such a special molecule – specific chemical and structural features of RNA
RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair
Ribozymes (catalytically active RNAs) (Intro)
The Ribosome - the role and function of ribosomal RNAs and the central dogma of molecular biology
The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity
Protein independent ribozymes – about Hammerhead, Varkud satellite, hairpin ribozyme & Co
RNA-based second messengers
Riboregulation and virulence, targeting by antibiotics
Juan J Quereda, Pascale Cossart
Regulating Bacterial Virulence with RNA.
Annu Rev Microbiol: 2017, 71;263-280
[PubMed:28886688]
[WorldCat.org]
[DOI]
(I p)
Petra Dersch, Muna A Khan, Sabrina Mühlen, Boris Görke
Roles of Regulatory RNAs for Antibiotic Resistance in Bacteria and Their Potential Value as Novel Drug Targets.
Front Microbiol: 2017, 8;803
[PubMed:28529506]
[WorldCat.org]
[DOI]
(P e)
Hao Wang, Paul A Mann, Li Xiao, Charles Gill, Andrew M Galgoci, John A Howe, Artjohn Villafania, Christopher M Barbieri, Juliana C Malinverni, Xinwei Sher, Todd Mayhood, Megan D McCurry, Nicholas Murgolo, Amy Flattery, Matthias Mack, Terry Roemer
Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.
Cell Chem Biol: 2017, 24(5);576-588.e6
[PubMed:28434876]
[WorldCat.org]
[DOI]
(I p)
Andreas Matern, Danielle Pedrolli, Stephanie Großhennig, Jörgen Johansson, Matthias Mack
Uptake and Metabolism of Antibiotics Roseoflavin and 8-Demethyl-8-Aminoriboflavin in Riboflavin-Auxotrophic Listeria monocytogenes.
J Bacteriol: 2016, 198(23);3233-3243
[PubMed:27672192]
[WorldCat.org]
[DOI]
(I e)
Aaron M Nuss, Ann Kathrin Heroven, Petra Dersch
RNA Regulators: Formidable Modulators of Yersinia Virulence.
Trends Microbiol: 2017, 25(1);19-34
[PubMed:27651123]
[WorldCat.org]
[DOI]
(I p)
Daniel Dar, Maya Shamir, J R Mellin, Mikael Koutero, Noam Stern-Ginossar, Pascale Cossart, Rotem Sorek
Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria.
Science: 2016, 352(6282);aad9822
[PubMed:27120414]
[WorldCat.org]
[DOI]
(I p)
John A Howe, Hao Wang, Thierry O Fischmann, Carl J Balibar, Li Xiao, Andrew M Galgoci, Juliana C Malinverni, Todd Mayhood, Artjohn Villafania, Ali Nahvi, Nicholas Murgolo, Christopher M Barbieri, Paul A Mann, Donna Carr, Ellen Xia, Paul Zuck, Dan Riley, Ronald E Painter, Scott S Walker, Brad Sherborne, Reynalda de Jesus, Weidong Pan, Michael A Plotkin, Jin Wu, Diane Rindgen, John Cummings, Charles G Garlisi, Rumin Zhang, Payal R Sheth, Charles J Gill, Haifeng Tang, Terry Roemer
Selective small-molecule inhibition of an RNA structural element.
Nature: 2015, 526(7575);672-7
[PubMed:26416753]
[WorldCat.org]
[DOI]
(I p)
Riboswitches
Protein- or tRNA-controlled RNA switches
RNA thermometers
The RNA world and evolution
RNA modification
Baixing Wu, Li Li, Ying Huang, Jinbiao Ma, Jinrong Min
##Title##
Curr Opin Struct Biol: 2017, 47;67-76
[PubMed:28624569]
[WorldCat.org]
[DOI]
(I p)
Hiroyuki Hori
Transfer RNA methyltransferases with a SpoU-TrmD (SPOUT) fold and their modified nucleosides in tRNA.
Biomolecules: 2017, 7(1);
[PubMed:28264529]
[WorldCat.org]
[DOI]
(I e)
Ajay K Rana, Serge Ankri
Reviving the RNA World: An Insight into the Appearance of RNA Methyltransferases.
Front Genet: 2016, 7;99
[PubMed:27375676]
[WorldCat.org]
[DOI]
(P e)
Marcus Fislage, Lina Wauters, Wim Versées
Invited review: MnmE, a GTPase that drives a complex tRNA modification reaction.
Biopolymers: 2016, 105(8);568-79
[PubMed:26832457]
[WorldCat.org]
[DOI]
(I p)
Clément Dégut, Luc Ponchon, Marcia Folly-Klan, Pierre Barraud, Carine Tisné
The m1A(58) modification in eubacterial tRNA: An overview of tRNA recognition and mechanism of catalysis by TrmI.
Biophys Chem: 2016, 210;27-34
[PubMed:26189113]
[WorldCat.org]
[DOI]
(I p)
RNA degradation/processing
John C Zinder, Christopher D Lima
Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors.
Genes Dev: 2017, 31(2);88-100
[PubMed:28202538]
[WorldCat.org]
[DOI]
(I p)
Soraya Aït-Bara, Agamemnon J Carpousis
RNA degradosomes in bacteria and chloroplasts: classification, distribution and evolution of RNase E homologs.
Mol Microbiol: 2015, 97(6);1021-135
[PubMed:26096689]
[WorldCat.org]
[DOI]
(I p)
Jonathan Houseley, David Tollervey
The many pathways of RNA degradation.
Cell: 2009, 136(4);763-76
[PubMed:19239894]
[WorldCat.org]
[DOI]
(I p)
Regulation by non-coding RNA
RNA dependent DNA Polymerases - from telomerase to retroviruses
RNA dependent RNA Polymerases – the RNA replicase
CRISPR/Cas: Science – the bacterial “immune” system
CRISPR/Cas: Application and groundbreaking perspectives
The mysterious function and role of 6S-RNA and pRNA in bacteria
Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer
Outlook: Finding function in mystery transcripts – eRNAs, long-non coding (lncRNA) and circular RNA (circRNA)
Outlook: RNA and SELEX – new prospects and applications for targeted interference with regulatory pathways