RplL

• Description: ribosomal protein
  
  

Gene name	rplL
Synonyms
Essential	yes PubMed
Product	ribosomal protein L12 (BL9)
Function	translation
Gene expression levels in SubtiExpress: rplL
Interactions involving this protein in SubtInteract: RplL
MW, pI	12 kDa, 4.355
Gene length, protein length	369 bp, 123 aa
Immediate neighbours	rplJ, ybxB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation, essential genes, membrane proteins, most abundant proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU01050

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU01050

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ribosomal protein L12P family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • YsxC-RplL PubMed
  • FusA-RplL PubMed
  • L10-L12₄ PubMed

• Localization: membrane associated PubMed

Database entries

• BsubCyc: BSU01050

• Structure:

• UniProt: P02394

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: rplJ-rplL PubMed

• Expression browser: rplL PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed
  • termination/ antitermination (L10-L12₄ complex) PubMed

• Regulatory mechanism:
  • L10-L12₄ complex: transcription termination (attenuation) at excess of the complex (autorepression) PubMed

• Additional information:
  • belongs to the 100 most abundant proteins PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 24809 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 142727 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 20697 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 11499 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 19060 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: