fusA
168
elongation factor G, catalyzes translocation steps of the ribosome after peptide bond formation, facilitates movement of tRNA and mRNA by one codon
Locus
BSU_01120
Molecular weight
76.36 kDa
Isoelectric point
4.61
Function
translation
Product
elongation factor G
Essential
yes
Synonyms
fusA, fus
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0480 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
130,684 132,762
Phenotypes of a mutant
The protein
Catalyzed reaction/ biological activity
hydrolyses GTP
catalyzes translocation steps of the ribosome after peptide bond formation, facilitates movement of tRNA and mRNA by one codon PubMed
Protein family
TRAFAC class translation factor GTPase superfamily (according to UniProt)
Classic translation factor GTPase family (according to UniProt)
tr-type G domain (aa 8-282) (according to UniProt)
Structure
2XEX (PDB) (from Staphylococcus aureus, 78.35% identity) PubMed
1ELO (PDB) (from Thermus thermophilus) PubMed
4BTC (PDB), 4BTD (PDB), the Thermus thermophilus EF-Gribosome complex in a pretranslocation state PubMed
Modification
phosphorylation on Ser-213 AND Ser-302 AND Ser-569 AND Ser-680 AND (Thr-24 OR Thr-25) AND (Thr-43 OR Ser 48) PubMed, PubMed
phosphorylated on Tyr-339 PubMed
cytoplasm (according to UniProt)
Additional information
belongs to the 100 most abundant proteins PubMed
Expression and Regulation
Operons
Description
Regulation
Regulatory mechanism
stringent response: negative regulation, PubMed, in stringent response
Biological materials
Expression vectors
References
Reviews
Loading
Original Publications
Loading
Page visits: 6222
Time of last update: 2025-02-24 20:47:29
Author of last update: Jstuelk