GerE

• Description: transcriptional regulator (repressor or activator) of a subset of sigma-K-dependent late spore coat genes
  
  

Gene name	gerE
Synonyms
Essential	no
Product	transcriptional regulator (LuxR-FixJ family)
Function	regulation of SigK-dependent gene expression
Gene expression levels in SubtiExpress: gerE
Function and regulation of this protein in SubtiPathways: gerE
Metabolic function and regulation of this protein in SubtiPathways: GerE
MW, pI	8 kDa, 9.635
Gene length, protein length	222 bp, 74 aa
Immediate neighbours	ysmB, ysmA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, germination

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU28410

Phenotypes of a mutant

• unable to germinate efficiently PubMed

Database entries

• BsubCyc: BSU28410

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LuxR-FixJ family of transcription regulators

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU28410

• Structure: 1FSE

• UniProt: P11470

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerE PubMed

• Expression browser: gerE PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Arthur Aronson, Purdue University, West Lafayette, USA homepage
• Charles Moran, Emory University, NC, USA homepage