msmX

msmX
168

multiple sugar ABC transporter (ATP-binding protein)

Locus
BSU_38810
Molecular weight
41.21 kDa
Isoelectric point
7.39
Protein length
365 aaSequenceBlast
Gene length
1098 bpSequenceBlast
Function
uptake of maltodextrin, melibiose (probably), and galactooligosaccharides
Product
multiple sugar ABC transporter (ATP-binding protein)
Essential
no
Synonyms
msmX, yxkG
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3839 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,984,133  3,985,230
Phenotypes of a mutant
no growth with pectin or galactan as single carbon source PubMed
The protein
Protein family
ABC transporter superfamily (according to UniProt)
Domains
ABC transporter domain (aa 4-235) (according to UniProt)
Structure
1G29 (PDB) (from Thermococcus litoralis, 54% identity) PubMed
P94360 (AlphaFold)
Paralogous protein(s)
FrlP, OpuBA
Localization
septal at the cell membrane PubMed
septal localization partially depends on the proton motive force PubMed
Noc and the Min system ensure the efficient utilization of the division site at midcell in by ensuring Z ring]] placement PubMed
FtsZ is anchored to the cell membrane by either FtsA or SepF PubMed"],"Additional information":["the novel antibiotic ADEP (acyldepsipeptides) causes FtsZ degradation via dysregulation ClpP activity (activity occurs even in the absence of an ATPase subunit (ClpC, ClpE, or ClpX)) PubMed
FtsZ is unfolded for N-terminal degradation by antibiotic-activated ClpP PubMed
Expression and Regulation
Operons
Genes
yxkF-msmX
Description
PubMed
Regulation
repressed by glucose (CcpA) PubMed
Expression
expression is heterogeneous PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
Open in new tab

yxkF→msmX

2025-04-07 03:27:05

Jstuelk

81

AF2FCB62C3853F05544C97E9ABCDF316421AD12D

84C66B43C7822D0A3BB4809B557110959136271B

Biological materials
Mutant
MGNA-B741 (msmX::erm), available at the NBRP B. subtilis, Japan
BKE38810 (msmX::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTAACATCCCCCTTTGT,  downstream forward: _UP4_TAAGATCAAAAAAACCGGAC
BKK38810 (msmX::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTAACATCCCCCTTTGT,  downstream forward: _UP4_TAAGATCAAAAAAACCGGAC
References
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434F6C546F783503A82D390FD238F05025FC1802

Page visits: 5649

Time of last update: 2025-04-13 19:17:33

Author of last update: Jstuelk