PdxT

• Description: pyridoxal-5'-phosphate synthase (glutaminase domain)
  
  

Gene name	pdxT
Synonyms	yaaE
Essential	no
Product	pyridoxal-5'-phosphate synthase (glutaminase domain)
Function	pyridoxal-5'-phosphate biosynthesis
Gene expression levels in SubtiExpress: pdxT
Interactions involving this protein in SubtInteract: PdxT
Metabolic function and regulation of this protein in SubtiPathways: PdxT
MW, pI	21 kDa, 4.984
Gene length, protein length	588 bp, 196 aa
Immediate neighbours	pdxS, serS
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

• Locus tag: BSU00120

Database entries

• BsubCyc: BSU00120

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: glutamine amidotransferase pdxT/SNO family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • PdxS-PdxT PubMed1 PubMed2

• Localization:

Database entries

• BsubCyc: BSU00120

• Structure:
  • PdxT 2NV0 PubMed
  • PdxS-PdxT complex 2NV2 PubMed

• UniProt: P37528

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: pdxS-pdxT PubMed

• Expression browser: pdxT PubMed

• Sigma factor:

• Regulation: negatively controlled by Spo0A PubMed
  • repressed under conditions that trigger sporulation (Spo0A) PubMed

• Regulatory mechanism:
  • Spo0A: transcription repression PubMed

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 1683 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 3958 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: