Difference between revisions of "YhdN"

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(The gene)
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU09530&redirect=T BSU09530]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yhdNO.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yhdNO.html]
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU09530&redirect=T BSU09530]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1PZ1 1PZ1]
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1PZ1 1PZ1]

Revision as of 13:18, 2 April 2014

  • Description: general stress protein, broad specificity aldo-keto reductase that converts MG to acetol

Gene name yhdN
Synonyms
Essential no
Product aldo/keto reductase, specific for NADP
Function detoxification of methylglyoxal
Gene expression levels in SubtiExpress: yhdN
Metabolic function and regulation of this protein in SubtiPathways:
yhdN
MW, pI 37 kDa, 4.77
Gene length, protein length 993 bp, 331 aa
Immediate neighbours sigM, plsC
Sequences Protein DNA DNA_with_flanks
Genetic context
YhdN context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YhdN expression.png















Categories containing this gene/protein

biosynthesis of lipids, general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU09530

Phenotypes of a mutant

  • increased sensitivity to methylglyoxal PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • methylglyoxal --> acetol PubMed
  • Protein family: aldo/keto reductase 2 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References