Difference between revisions of "Maf"

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* '''Description:''' cell division inhibitor in competent cells, blocks septation during the escape from competence, required for the stability of [[ComGA]]<br/><br/>
+
* '''Description:''' [[cell division]] inhibitor in competent cells, blocks septation during the escape from competence, required for the stability of [[ComGA]]<br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || cell division inhibitor  
+
|style="background:#ABCDEF;" align="center"| '''Product''' || [[cell division]] inhibitor  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || cell division control
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|style="background:#ABCDEF;" align="center"|'''Function''' || [[cell division]] control
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28050 maf]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28050 maf]
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[cell division]]}}
+
{{SubtiWiki category|[[cell division]]}},
 +
{{SubtiWiki category|[[genetic competence]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):''' binds phosphorylated compounds (UTP, IMP, IDP, GDP and others) in ''in vitro'' experiments
+
* '''[[Cofactors]]:''' binds phosphorylated compounds (UTP, IMP, IDP, GDP and others) in ''in vitro'' experiments
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
 +
** cytosolic protein {{PubMed|24164455}}
 
** near the poles of competent cells {{PubMed|21564336}}
 
** near the poles of competent cells {{PubMed|21564336}}
  
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=maf_2862572_2863141_-1 maf] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=maf_2862572_2863141_-1 maf] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''   
 
* '''Regulation:'''   
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==Original publications==
 
==Original publications==
'''Additional publications:''' {{PubMed|21926231}}
+
<pubmed> 21564336 10841541 8387996 11948146 24164455 21926231</pubmed>
<pubmed> 21564336 10841541 8387996 11948146 </pubmed>
 
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:53, 16 March 2014

  • Description: cell division inhibitor in competent cells, blocks septation during the escape from competence, required for the stability of ComGA

Gene name maf
Synonyms
Essential no
Product cell division inhibitor
Function cell division control
Gene expression levels in SubtiExpress: maf
Interactions involving this protein in SubtInteract: Maf
MW, pI 21 kDa, 5.711
Gene length, protein length 567 bp, 189 aa
Immediate neighbours radC, spoIIB
Sequences Protein DNA DNA_with_flanks
Genetic context
Maf context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Maf expression.png















Categories containing this gene/protein

cell division, genetic competence

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU28050

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: maf family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Cofactors: binds phosphorylated compounds (UTP, IMP, IDP, GDP and others) in in vitro experiments
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • expressed when cells enter the compentent state (ComK) PubMed
    • expression is reduced in a SigV mutant PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

PubMed

Original publications