HelP

• Description: helicase processivity factor
  
  

Gene name	ydcP
Synonyms	ydcP
Essential	no
Product	helicase processivity factor
Function	conjugation and replication of ICEBs1
Gene expression levels in SubtiExpress: helP
MW, pI	13 kDa, 5.309
Gene length, protein length	378 bp, 126 aa
Immediate neighbours	ydcO, ydcQ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

mobile genetic elements

The gene

Basic information

• Locus tag: BSU04850

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • enables the host-encoded helicase PcrA to unwind the double-stranded ICEBs1 DNA PubMed
• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P96633

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: helP PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • A ncRNA is predicted between ydcO and helP PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Jacob Thomas, Catherine A Lee, Alan D Grossman
A conserved helicase processivity factor is needed for conjugation and replication of an integrative and conjugative element.
PLoS Genet: 2013, 9(1);e1003198
[PubMed:23326247] [WorldCat.org] [DOI] (I p)

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)