Difference between revisions of "HelD"
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| − | * '''Description:''' DNA 3'-5' helicase IV<br/><br/> | + | * '''Description:''' DNA 3'-5' helicase IV, stimulates transcription in an ATP-dependent manner by enhancing transcriptional cycling and elongation <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Product''' || DNA 3'-5' helicase IV | |style="background:#ABCDEF;" align="center"| '''Product''' || DNA 3'-5' helicase IV | ||
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair | + | |style="background:#ABCDEF;" align="center"|'''Function''' || [[transcription]], [[DNA repair/ recombination]] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33450 helD] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33450 helD] | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[DNA repair/ recombination]]}} | + | {{SubtiWiki category|[[DNA repair/ recombination]]}}, |
| + | {{SubtiWiki category|[[transcription]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=helD_3434327_3436651_-1 helD] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=helD_3434327_3436651_-1 helD] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Mutant:''' | * '''Mutant:''' | ||
| − | ** 1A899 ( ''helD''::''erm'') | + | ** 1A899 ( ''helD''::''erm''), available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A899&Search=1A899 BGSC] |
* '''Expression vector:''' | * '''Expression vector:''' | ||
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=References= | =References= | ||
| − | <pubmed>11544244 21710567 </pubmed> | + | <pubmed>11544244 21710567 24520113</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:45, 13 February 2014
- Description: DNA 3'-5' helicase IV, stimulates transcription in an ATP-dependent manner by enhancing transcriptional cycling and elongation
| Gene name | helD |
| Synonyms | yvgS |
| Essential | no |
| Product | DNA 3'-5' helicase IV |
| Function | transcription, DNA repair/ recombination |
| Gene expression levels in SubtiExpress: helD | |
| MW, pI | 89 kDa, 6.083 |
| Gene length, protein length | 2322 bp, 774 aa |
| Immediate neighbours | cysI, yvgT |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
DNA repair/ recombination, transcription
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU33450
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: UvrD subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Interactions:
- HelD interacts with the RNA polymerase PubMed
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O32215
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- 1A899 ( helD::erm), available at BGSC
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
