Difference between revisions of "YjbH"

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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* increased thermotolerance due to increased stabiliy of [[Spx]] and thus increased expression of ''[[trxA]]'' {{PubMed|24417481}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''contains Zn atoms (coordinated by the N-terminal His-rich region) [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed]
+
* '''[[Cofactors]]:'''
 +
** contains Zn atoms (coordinated by the N-terminal His-rich region) [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed]
  
 
* '''Effectors of protein activity:'''  
 
* '''Effectors of protein activity:'''  
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=References=
 
=References=
 
==Reviews==
 
==Reviews==
'''Additional reviews:''' {{PubMed|23479438,19609260}}
+
<pubmed> 23375660 23479438,19609260</pubmed>
<pubmed> 23375660 </pubmed>
 
 
==Original Publications==
 
==Original Publications==
'''Additional publications:''' {{PubMed|21378193,21947404}}
+
<pubmed>17293416, 19074380 17908206, 20525796 21378193,21947404 24417481</pubmed>
<pubmed>17293416, 19074380 17908206, 20525796 </pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 09:33, 16 January 2014

  • Description: adaptor protein for ClpX-ClpP-catalyzed Spx degradation, confers resistance against nitrosating agents

Gene name yjbH
Synonyms
Essential no
Product adaptor protein
Function stimulation of Spx degradation
Gene expression levels in SubtiExpress: yjbH
Interactions involving this protein in SubtInteract: YjbH
MW, pI 31 kDa, 5.206
Gene length, protein length 825 bp, 275 aa
Immediate neighbours yizD, yjbI
Sequences Protein DNA DNA_with_flanks
Genetic context
YjbH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YjbH expression.png















Categories containing this gene/protein

proteolysis, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU11550

Phenotypes of a mutant

  • increased thermotolerance due to increased stabiliy of Spx and thus increased expression of trxA PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: adaptor protein for ClpX-ClpP-catalyzed Spx degradation PubMed
  • Protein family: UPF0413 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Cofactors:
    • contains Zn atoms (coordinated by the N-terminal His-rich region) PubMed
  • Effectors of protein activity:
    • Zn atom is released upon treatment with strong oxidants PubMed
    • interaction with YirB inhibits the formation of a complex with Spx PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Peter Zuber, Oregon Health and Science University, USA Homepage

Claes von Wachenfeldt, Lund University, Sweden Homepage

Your additional remarks

References

Reviews

Original Publications