YerD

• Description: general stress protein, similar to glutamate synthase (ferredoxin)
  
  

Gene name	yerD
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yerD
MW, pI	58 kDa, 7.349
Gene length, protein length	1575 bp, 525 aa
Immediate neighbours	yerC, pcrB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), poorly characterized/ putative enzymes, membrane proteins

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU06590

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): GltA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to UniProt)

Database entries

• Structure:

• UniProt: O34849

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yerD PubMed

• Expression browser: yerD PubMed

• Sigma factor: SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed
  • strongly induced in response to glucose starvation in M9 medium PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: GP1184 (tet) available in Jörg Stülke's lab

• Expression vector: pBP32 (expression vector for E. coli BL21; N-terminal Strep-tag-YerD fusion protein, based on pGP172), available in Fabian Commichau's lab

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• FLAG-tag construct: GP1187 (spc, based on pGP1331), available in Jörg Stülke's lab

• Antibody:

Labs working on this gene/protein

Fabian Commichau University of Göttingen, Germany Homepage