Difference between revisions of "Noc"
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=noc_4207897_4208748_-1 noc] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=noc_4207897_4208748_-1 noc] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** constitutively expressed {{PubMed|23701187}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
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<pubmed> 19680248 19884039 </pubmed> | <pubmed> 19680248 19884039 </pubmed> | ||
==Original Publications== | ==Original Publications== | ||
| − | <pubmed>16549676,11807071,19494834,15210112,11948146 , 22457634</pubmed> | + | <pubmed>16549676,11807071,19494834,15210112,11948146 , 22457634 23701187</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:00, 27 May 2013
- Description: DNA-binding protein, spatial regulator of cell division to protect the nucleoid, and timing device with an important role in the coordination of chromosome segregation and cell division, Noc and the Min system ensure the efficient utilization of the division site at midcell in by ensuring Z ring placement
| Gene name | noc |
| Synonyms | yyaA |
| Essential | no |
| Product | effector of nucleoid occlusion |
| Function | control of cell division |
| Gene expression levels in SubtiExpress: noc | |
| MW, pI | 32 kDa, 5.812 |
| Gene length, protein length | 849 bp, 283 aa |
| Immediate neighbours | yyaB, rsmG |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40990
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds specific sites on the chromosome PubMed
- Protein family: ParB family (according to Swiss-Prot)
- Paralogous protein(s): Spo0J
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P37524
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- constitutively expressed PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion: available in the Jeff Errington lab
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Jeff Errington, Newcastle, UK Homepage
Your additional remarks
References
Reviews
Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039]
[WorldCat.org]
[DOI]
(I p)
David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248]
[WorldCat.org]
[DOI]
(I p)
Original Publications
