Difference between revisions of "PbuE"

From SubtiWiki
Jump to: navigation, search
Line 26: Line 26:
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
−
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pbuE_625125_626291_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:pbuE_expression.png|500px]]
+
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pbuE_625125_626291_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:pbuE_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU05800]]
 
|-
 
|-
 
|}
 
|}

Revision as of 12:39, 16 May 2013

  • Description: putative hypoxanthine exporter

Gene name pbuE
Synonyms ydhL
Essential no
Product putative hypoxanthine exporter
Function nucleotide metabolism
Gene expression levels in SubtiExpress: pbuE
MW, pI 41 kDa, 8.884
Gene length, protein length 1164 bp, 388 aa
Immediate neighbours ydhK, gmuB
Sequences Protein DNA DNA_with_flanks
Genetic context
YdhL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PbuE expression.png
























Categories containing this gene/protein

transporters/ other, nucleotide metabolism/ other, membrane proteins

This gene is a member of the following regulons

A-box

The gene

Basic information

  • Locus tag: BSU05800

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jean-François Lemay, Guillaume Desnoyers, Simon Blouin, Benoit Heppell, Laurène Bastet, Patrick St-Pierre, Eric Massé, Daniel A Lafontaine
Comparative study between transcriptionally- and translationally-acting adenine riboswitches reveals key differences in riboswitch regulatory mechanisms.
PLoS Genet: 2011, 7(1);e1001278
[PubMed:21283784] [WorldCat.org] [DOI] (I e)

Vanessa Delfosse, Patricia Bouchard, Eric Bonneau, Pierre Dagenais, Jean-François Lemay, Daniel A Lafontaine, Pascale Legault
Riboswitch structure: an internal residue mimicking the purine ligand.
Nucleic Acids Res: 2010, 38(6);2057-68
[PubMed:20022916] [WorldCat.org] [DOI] (I p)

Elias Seif, Sidney Altman
RNase P cleaves the adenine riboswitch and stabilizes pbuE mRNA in Bacillus subtilis.
RNA: 2008, 14(6);1237-43
[PubMed:18441052] [WorldCat.org] [DOI] (I p)

Natalia P Zakataeva, Sergey V Gronskiy, Anastasia S Sheremet, Ekaterina A Kutukova, Anna E Novikova, Vitaliy A Livshits
A new function for the Bacillus PbuE purine base efflux pump: efflux of purine nucleosides.
Res Microbiol: 2007, 158(8-9);659-65
[PubMed:17935948] [WorldCat.org] [DOI] (P p)

K V Lobanov, N V Korol'kova, S Iu Eremina, L Errais Lopes, S A Proshkin, A S Mironov
[Mutations altering the specificity of the sensor RNA encoded by the Bacillus subtilis pbuE gene].
Genetika: 2007, 43(6);859-64
[PubMed:17853814] [WorldCat.org] (P p)

Jean-François Lemay, J Carlos Penedo, Renaud Tremblay, David M J Lilley, Daniel A Lafontaine
Folding of the adenine riboswitch.
Chem Biol: 2006, 13(8);857-68
[PubMed:16931335] [WorldCat.org] [DOI] (P p)

J Kenneth Wickiser, Ming T Cheah, Ronald R Breaker, Donald M Crothers
The kinetics of ligand binding by an adenine-sensing riboswitch.
Biochemistry: 2005, 44(40);13404-14
[PubMed:16201765] [WorldCat.org] [DOI] (P p)

Per Nygaard, Hans H Saxild
The purine efflux pump PbuE in Bacillus subtilis modulates expression of the PurR and G-box (XptR) regulons by adjusting the purine base pool size.
J Bacteriol: 2005, 187(2);791-4
[PubMed:15629952] [WorldCat.org] [DOI] (P p)

Maumita Mandal, Ronald R Breaker
Adenine riboswitches and gene activation by disruption of a transcription terminator.
Nat Struct Mol Biol: 2004, 11(1);29-35
[PubMed:14718920] [WorldCat.org] [DOI] (P p)

Lars Engholm Johansen, Per Nygaard, Catharina Lassen, Yvonne Agersø, Hans H Saxild
Definition of a second Bacillus subtilis pur regulon comprising the pur and xpt-pbuX operons plus pbuG, nupG (yxjA), and pbuE (ydhL).
J Bacteriol: 2003, 185(17);5200-9
[PubMed:12923093] [WorldCat.org] [DOI] (P p)

Maumita Mandal, Benjamin Boese, Jeffrey E Barrick, Wade C Winkler, Ronald R Breaker
Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria.
Cell: 2003, 113(5);577-86
[PubMed:12787499] [WorldCat.org] [DOI] (P p)

Retrieved from "http://subtiwiki.uni-goettingen.de/wiki//index.php?title=PbuE&oldid=188605"