Difference between revisions of "IspE"

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Revision as of 12:18, 16 May 2013

  • Description: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Gene name ispE
Synonyms yabH , ipk
Essential yes PubMed
Product 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Function isoprenoid biosynthesis
Gene expression levels in SubtiExpress: ispE
MW, pI 31 kDa, 6.349
Gene length, protein length 867 bp, 289 aa
Immediate neighbours sspF, purR
Sequences Protein DNA DNA_with_flanks
Genetic context
IspE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
IspE expression.png
























Categories containing this gene/protein

biosynthesis of lipids, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU00460

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol (according to Swiss-Prot)
  • Protein family: IspE subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References