Difference between revisions of "SpoIID"
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|style="background:#ABCDEF;" align="center"|'''Function''' || dissolution of the septal cell wall | |style="background:#ABCDEF;" align="center"|'''Function''' || dissolution of the septal cell wall | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36750 spoIID] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SpoIID SpoIID] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SpoIID SpoIID] | ||
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywmC]]'', ''[[murAA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywmC]]'', ''[[murAA]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36750 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36750 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36750 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:spoIID_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:spoIID_context.gif]] | ||
Revision as of 14:04, 13 May 2013
- Description: cell wall hydrolase (lytic transglycosylase), required for complete dissolution of the asymmetric septum
| Gene name | spoIID |
| Synonyms | spoIIC |
| Essential | no |
| Product | lytic transglycosylase |
| Function | dissolution of the septal cell wall |
| Gene expression levels in SubtiExpress: spoIID | |
| Interactions involving this protein in SubtInteract: SpoIID | |
| MW, pI | 37 kDa, 9.764 |
| Gene length, protein length | 1029 bp, 343 aa |
| Immediate neighbours | ywmC, murAA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall/ other, sporulation proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU36750
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: degrades the glycan strands of the peptidoglycan into disaccharide units PubMed, enhances SpoIIP activity PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane PubMed
Database entries
- Structure:
- UniProt: P07372
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: spoIID PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Pablo Meyer, Jennifer Gutierrez, Kit Pogliano, Jonathan Dworkin
Cell wall synthesis is necessary for membrane dynamics during sporulation of Bacillus subtilis.
Mol Microbiol: 2010, 76(4);956-70
[PubMed:20444098]
[WorldCat.org]
[DOI]
(I p)
Jennifer Gutierrez, Rachelle Smith, Kit Pogliano
SpoIID-mediated peptidoglycan degradation is required throughout engulfment during Bacillus subtilis sporulation.
J Bacteriol: 2010, 192(12);3174-86
[PubMed:20382772]
[WorldCat.org]
[DOI]
(I p)
Cecile Morlot, Tsuyoshi Uehara, Kathleen A Marquis, Thomas G Bernhardt, David Z Rudner
A highly coordinated cell wall degradation machine governs spore morphogenesis in Bacillus subtilis.
Genes Dev: 2010, 24(4);411-22
[PubMed:20159959]
[WorldCat.org]
[DOI]
(I p)
Arnaud Chastanet, Richard Losick
Engulfment during sporulation in Bacillus subtilis is governed by a multi-protein complex containing tandemly acting autolysins.
Mol Microbiol: 2007, 64(1);139-52
[PubMed:17376078]
[WorldCat.org]
[DOI]
(P p)
Thierry Doan, Kathleen A Marquis, David Z Rudner
Subcellular localization of a sporulation membrane protein is achieved through a network of interactions along and across the septum.
Mol Microbiol: 2005, 55(6);1767-81
[PubMed:15752199]
[WorldCat.org]
[DOI]
(P p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836]
[WorldCat.org]
[DOI]
(I p)
P Eichenberger, P Fawcett, R Losick
A three-protein inhibitor of polar septation during sporulation in Bacillus subtilis.
Mol Microbiol: 2001, 42(5);1147-62
[PubMed:11886548]
[WorldCat.org]
[DOI]
(P p)
A Driks, R Losick
Compartmentalized expression of a gene under the control of sporulation transcription factor sigma E in Bacillus subtilis.
Proc Natl Acad Sci U S A: 1991, 88(22);9934-8
[PubMed:1946462]
[WorldCat.org]
[DOI]
(P p)
I Lopez-Diaz, S Clarke, J Mandelstam
spoIID operon of Bacillus subtilis: cloning and sequence.
J Gen Microbiol: 1986, 132(2);341-54
[PubMed:3011962]
[WorldCat.org]
[DOI]
(P p)
