Difference between revisions of "CotS"

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|style="background:#ABCDEF;" align="center"|'''Function''' || resistance of the spore  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance of the spore  
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU30900 cotS]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30900 cotS]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 40 kDa, 6.641   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 40 kDa, 6.641   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytxO]]'', ''[[cotSA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytxO]]'', ''[[cotSA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15068&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU30900 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU30900 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU30900 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:cotS_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:cotS_context.gif]]

Revision as of 13:41, 13 May 2013

  • Description: spore coat protein

Gene name cotS
Synonyms
Essential no
Product spore coat protein
Function resistance of the spore
Gene expression levels in SubtiExpress: cotS
MW, pI 40 kDa, 6.641
Gene length, protein length 1053 bp, 351 aa
Immediate neighbours ytxO, cotSA
Sequences Protein DNA Advanced_DNA
Genetic context
CotS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotS expression.png
























Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

  • Locus tag: BSU30900

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: cotS family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Ritsuko Kuwana, Hiromi Ikejiri, Satoko Yamamura, Hiromu Takamatsu, Kazuhito Watabe
Functional relationship between SpoVIF and GerE in gene regulation during sporulation of Bacillus subtilis.
Microbiology (Reading): 2004, 150(Pt 1);163-170
[PubMed:14702409] [WorldCat.org] [DOI] (P p)

S Little, A Driks
Functional analysis of the Bacillus subtilis morphogenetic spore coat protein CotE.
Mol Microbiol: 2001, 42(4);1107-20
[PubMed:11737650] [WorldCat.org] [DOI] (P p)

H Takamatsu, T Kodama, K Watabe
Assembly of the CotSA coat protein into spores requires CotS in Bacillus subtilis.
FEMS Microbiol Lett: 1999, 174(1);201-6
[PubMed:10234840] [WorldCat.org] [DOI] (P p)

H Takamatsu, Y Chikahiro, T Kodama, H Koide, S Kozuka, K Tochikubo, K Watabe
A spore coat protein, CotS, of Bacillus subtilis is synthesized under the regulation of sigmaK and GerE during development and is located in the inner coat layer of spores.
J Bacteriol: 1998, 180(11);2968-74
[PubMed:9603889] [WorldCat.org] [DOI] (P p)

Akiko Abe, Hidekatsu Koide, Takeyuki Kohno, Kazuhito Watabe
A Bacillus subtilis spore coat polypeptide gene, cotS.
Microbiology (Reading): 1995, 141 ( Pt 6);1433-1442
[PubMed:7545510] [WorldCat.org] [DOI] (P p)