Difference between revisions of "MutM"
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|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair | |style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29080 mutM] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 8.889 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 8.889 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytaF]]'', ''[[polA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytaF]]'', ''[[polA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29080 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29080 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29080 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:mutM_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:mutM_context.gif]] | ||
Revision as of 14:34, 13 May 2013
- Description: formamidopyrimidine-DNA glycosidase
| Gene name | mutM |
| Synonyms | ytaE |
| Essential | no |
| Product | formamidopyrimidine-DNA glycosidase |
| Function | DNA repair |
| Gene expression levels in SubtiExpress: mutM | |
| MW, pI | 31 kDa, 8.889 |
| Gene length, protein length | 834 bp, 278 aa |
| Immediate neighbours | ytaF, polA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29080
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine (according to Swiss-Prot)
- Protein family: FPG family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 2F5S (complex with oxoG:C, Geobacillus stearothermophilus)
- UniProt: O34403
- KEGG entry: [2]
- E.C. number: 3.2.2.23
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
