YneA

• Description: inhibits cell division during SOS response
  
  

Gene name	yneA
Synonyms
Essential	no
Product	cell division control protein
Function	inhibits cell division during SOS response
Gene expression levels in SubtiExpress: yneA
MW, pI	11 kDa, 4.613
Gene length, protein length	315 bp, 105 aa
Immediate neighbours	lexA, yneB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell division

This gene is a member of the following regulons

LexA regulon

The gene

Basic information

• Locus tag: BSU17860

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: yneA family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • LysM peptidoglycan binding domain PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • secreted to the medium (signal peptide) PubMed

Database entries

• Structure:

• UniProt: Q45056

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yneA-yneB-ynzC PubMed

• Expression browser: yneA PubMed

• Sigma factor:

• Regulation:
  • induced by DNA damage (LexA) PubMed

• Regulatory mechanism:
  • LexA: transcription repression PubMed

• Additional information:
  • YneA is rapidly degraded by extracellular proteases PubMed

Biological materials

• Mutant:
  • 1A1012 ( yneA::tet), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: