CotF

• Description: spore coat protein
  
  

Gene name	cotF
Synonyms
Essential	no
Product	spore coat protein
Function	resistance of the spore
Gene expression levels in SubtiExpress: cotF
MW, pI	18 kDa, 7.374
Gene length, protein length	480 bp, 160 aa
Immediate neighbours	yybS, hypR
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU40530

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: cotF family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • inner spore coat PubMed

Database entries

• Structure:

• UniProt: P23261

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotF (according to DBTBS)

• Expression browser: cotF PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:
  • 1S106 ( cotF::cat), PubMed, available at BGSC
  • 1S107 ( cotF::cat), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: