EfeO

• Description: elemental iron uptake system (permease)
  
  

Gene name	ywbM
Synonyms	ipa-28d
Essential	no
Product	elemental iron uptake system (permease)
Function	iron uptake
Metabolic function and regulation of this protein in SubtiPathways: Protein secretion
MW, pI	42 kDa, 4.712
Gene length, protein length	1155 bp, 385 aa
Immediate neighbours	ywbN, ywbL
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transporters/ other, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU38270

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: UPF0409 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: membrane associated PubMed

Database entries

• Structure:

• UniProt: P39596

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • ywbL-ywbM-ywbN PubMed

• Expression browser: ywbM PubMed

• Sigma factor:

• Regulation:
  • induced upon iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: