Difference between revisions of "FtsX"
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* '''Operon:''' ''[[ftsE]]-[[ftsX]]'' (according to [http://dbtbs.hgc.jp/COG/prom/ftsEX.html DBTBS]) | * '''Operon:''' ''[[ftsE]]-[[ftsX]]'' (according to [http://dbtbs.hgc.jp/COG/prom/ftsEX.html DBTBS]) | ||
| − | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ftsX_3623938_3624828_-1 ftsX] {{PubMed|22383849}} |
| + | |||
| + | * '''Sigma factor:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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** [[Spo0A]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ** [[Spo0A]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 07:30, 17 April 2012
- Description: ABC transporter (membrane protein) (FtsE-FtsX), required for proper activation of Spo0A and initiation of sporulation
| Gene name | ftsX |
| Synonyms | |
| Essential | no |
| Product | ABC transporter (membrane protein) |
| Function | initiation of sporulation |
| Interactions involving this protein in SubtInteract: FtsX | |
| MW, pI | 32 kDa, 10.016 |
| Gene length, protein length | 888 bp, 296 aa |
| Immediate neighbours | ctpB, ftsE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
ABC transporters, phosphorelay, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35250
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: FtsX subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed
Database entries
- Structure:
- UniProt: O34876
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711]
[WorldCat.org]
[DOI]
(I p)
Sharon Garti-Levi, Ronen Hazan, James Kain, Masaya Fujita, Sigal Ben-Yehuda
The FtsEX ABC transporter directs cellular differentiation in Bacillus subtilis.
Mol Microbiol: 2008, 69(4);1018-28
[PubMed:18573177]
[WorldCat.org]
[DOI]
(I p)
Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647]
[WorldCat.org]
[DOI]
(P p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
