NadD

• Description: nicotinamide-nucleotide adenylyltransferase
  
  

Gene name	nadD
Synonyms	yqeJ
Essential	yes PubMed
Product	nicotinamide-nucleotide adenylyltransferase
Function	NAD biosynthesis
MW, pI	22 kDa, 5.123
Gene length, protein length	567 bp, 189 aa
Immediate neighbours	yqeK, yqeI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis of cofactors, essential genes

The gene

Basic information

• Locus tag: BSU25640

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD⁺ (according to Swiss-Prot)

• Protein family: nadD family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1KAQ

• UniProt: P54455

• KEGG entry: [2]

• E.C. number: 2.7.7.18

Expression and regulation

• Operon:

• Expression browser: nadD PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Andrea M Olland, Kathryn W Underwood, Robert M Czerwinski, Mei-Chu Lo, Ann Aulabaugh, Joel Bard, Mark L Stahl, William S Somers, Francis X Sullivan, Rajiv Chopra
Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase.
J Biol Chem: 2002, 277(5);3698-707
[PubMed:11704676] [WorldCat.org] [DOI] (P p)