YokJ

• Description: putative antitoxin
  
  

Gene name	yokJ
Synonyms
Essential	no
Product	putative antitoxin
Function	inhibition of the cytotoxic activity of YokI
Interactions involving this protein in SubtInteract: YokJ
MW, pI	18 kDa, 4.134
Gene length, protein length	495 bp, 165 aa
Immediate neighbours	yokK, yokI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, SP-beta prophage

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

• Locus tag: BSU21570

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YokI-YokJ PubMed

• Localization:

Database entries

• Structure:

• UniProt: O31997

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yokI-yokJ-yokK-yokL PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Laura E Holberger, Fernando Garza-Sánchez, James Lamoureux, David A Low, Christopher S Hayes
A novel family of toxin/antitoxin proteins in Bacillus species.
FEBS Lett: 2012, 586(2);132-6
[PubMed:22200572] [WorldCat.org] [DOI] (I p)