CotO

• Description: spore coat morphogenetic protein, controls assembly of the coat layers and coat surface topography
  
  

Gene name	cotO
Synonyms	yjbX
Essential	no
Product	spore coat morphogenetic protein
Function	controls assembly of the coat layers and coat surface topography
MW, pI	25 kDa, 6.376
Gene length, protein length	681 bp, 227 aa
Immediate neighbours	fabI, cotZ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU11730

Phenotypes of a mutant

spores are defective in germination PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • spore wall (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O31622

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotO (according to DBTBS)

• Sigma factor: SigE PubMed

• Regulation:
  • repressed by casamino acids PubMed
  • expressed during sporulation in the mother cell PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: