Difference between revisions of "BslA"
| Line 1: | Line 1: | ||
| − | * '''Description:''' required for complex colony architecture<br/><br/> | + | * '''Description:''' required for complex colony architecture, facilitates biofilm matrix assembly<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || cell wall protein |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || pellicle formation | |style="background:#ABCDEF;" align="center"|'''Function''' || pellicle formation | ||
| Line 45: | Line 45: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * reduced colony complexity {{PubMed|21742882}} | ||
=== Database entries === | === Database entries === | ||
| Line 53: | Line 54: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| − | |||
=The protein= | =The protein= | ||
| Line 81: | Line 79: | ||
* '''Interactions:''' | * '''Interactions:''' | ||
| − | * '''Localization:''' | + | * '''Localization:''' |
| + | ** extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed] | ||
| + | ** cell wall {{PubMed|21742882}} | ||
=== Database entries === | === Database entries === | ||
| Line 104: | Line 104: | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[DegU]]-P: transcription activation {{PubMed|18978066}} | + | ** [[DegU]]-P: transcription activation {{PubMed|18978066}}, this might be indirect {{PubMed|21742882}} |
** [[AbrB]]: transcription repression {{PubMed|18978066}} | ** [[AbrB]]: transcription repression {{PubMed|18978066}} | ||
| Line 128: | Line 128: | ||
=References= | =References= | ||
| − | <pubmed> 18978066 18957862, 17850253 21097620 </pubmed> | + | <pubmed> 18978066 18957862, 17850253 21097620 21742882 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:25, 12 July 2011
- Description: required for complex colony architecture, facilitates biofilm matrix assembly
| Gene name | yuaB |
| Synonyms | |
| Essential | no |
| Product | cell wall protein |
| Function | pellicle formation |
| MW, pI | 19 kDa, 9.987 |
| Gene length, protein length | 543 bp, 181 aa |
| Immediate neighbours | yuaC, ktrA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31080
Phenotypes of a mutant
- reduced colony complexity PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
Database entries
- Structure:
- UniProt: P71014
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Adam Ostrowski, Angela Mehert, Alan Prescott, Taryn B Kiley, Nicola R Stanley-Wall
YuaB functions synergistically with the exopolysaccharide and TasA amyloid fibers to allow biofilm formation by Bacillus subtilis.
J Bacteriol: 2011, 193(18);4821-31
[PubMed:21742882]
[WorldCat.org]
[DOI]
(I p)
Akos T Kovács, Oscar P Kuipers
Rok regulates yuaB expression during architecturally complex colony development of Bacillus subtilis 168.
J Bacteriol: 2011, 193(4);998-1002
[PubMed:21097620]
[WorldCat.org]
[DOI]
(I p)
Daniel T Verhamme, Ewan J Murray, Nicola R Stanley-Wall
DegU and Spo0A jointly control transcription of two loci required for complex colony development by Bacillus subtilis.
J Bacteriol: 2009, 191(1);100-8
[PubMed:18978066]
[WorldCat.org]
[DOI]
(I p)
Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862]
[WorldCat.org]
[DOI]
(I p)
Kazuo Kobayashi
Gradual activation of the response regulator DegU controls serial expression of genes for flagellum formation and biofilm formation in Bacillus subtilis.
Mol Microbiol: 2007, 66(2);395-409
[PubMed:17850253]
[WorldCat.org]
[DOI]
(P p)
