Difference between revisions of "SigF"

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(Original Publications)
(This gene is a member of the following regulons)
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[AbrB regulon]]}},
 
{{SubtiWiki regulon|[[SigF regulon]]}},
 
{{SubtiWiki regulon|[[SigF regulon]]}},
 
{{SubtiWiki regulon|[[SigG regulon]]}},
 
{{SubtiWiki regulon|[[SigG regulon]]}},
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{{SubtiWiki regulon|[[SinR regulon]]}},
 
{{SubtiWiki regulon|[[SinR regulon]]}},
 
{{SubtiWiki regulon|[[Spo0A regulon]]}}
 
{{SubtiWiki regulon|[[Spo0A regulon]]}}
 +
 
=The [[SigF regulon]]=
 
=The [[SigF regulon]]=
 
=The gene=
 
=The gene=

Revision as of 16:45, 8 July 2011

Gene name sigF
Synonyms spoIIAC
Essential no
Product RNA polymerase forespore-specific
(early) sigma factor SigF
Function transcription of sporulation genes (late mother cell)
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 29 kDa, 5.078
Gene length, protein length 765 bp, 255 aa
Immediate neighbours spoVAA, spoIIAB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SigF context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

transcription, sigma factors and their control, sporulation proteins, membrane proteins

This gene is a member of the following regulons

AbrB regulon, SigF regulon, SigG regulon, SigH regulon, SinR regulon, Spo0A regulon

The SigF regulon

The gene

Basic information

  • Locus tag: BSU23450

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: sigma-70 factor family (according to Swiss-Prot)
  • Paralogous protein(s):

Genes controlled by SigF

dacF-spoIIAA-spoIIAB-sigF, sigG, pbpF, yphA-seaA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure: 1L0O (complex with SpoIIAB, Geobacillus stearothermophilus)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by casamino acids PubMed
    • dacF: expressed during sporulation
    • spoIIAA: expressed early during sporulation
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Michiel J L de Hoon, Patrick Eichenberger, Dennis Vitkup
Hierarchical evolution of the bacterial sporulation network.
Curr Biol: 2010, 20(17);R735-45
[PubMed:20833318] [WorldCat.org] [DOI] (I p)

The SigF regulon

Original Publications

Additional publications: PubMed