Difference between revisions of "ParA"
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| − | * '''Description:''' centromere-like function involved in forespore chromosome partitioning / negative regulation of sporulation initiation <br/><br/> | + | * '''Description:''' ATPase, centromere-like function involved in forespore chromosome partitioning / negative regulation of sporulation initiation <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 62: | Line 62: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' regulates [[DNA replication]] initiation by either inhibiting or activating the [[DNA replication]] initiator protein [[DnaA]] {{PubMed|21235642}} |
* '''Protein family:''' parA family (according to Swiss-Prot) | * '''Protein family:''' parA family (according to Swiss-Prot) | ||
| Line 78: | Line 78: | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' |
| + | ** [[Spo0J]] inhibits [[Soj]] dimerization and concomitant DNA-binding activity by stimulating Soj ATPase activity {{PubMed|21235642}} | ||
* '''Interactions:''' | * '''Interactions:''' | ||
| + | ** [[Spo0J]]-[[Soj]] {{PubMed|21235642}} | ||
| + | |||
* '''Localization:''' | * '''Localization:''' | ||
| Line 133: | Line 136: | ||
<pubmed> 20157337 </pubmed> | <pubmed> 20157337 </pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | <pubmed>15659156,11532141,19450516,18854156,10619015,8866474,12492861,9701805,12950914,14651647, 19450516 20566861 </pubmed> | + | <pubmed>15659156,11532141,19450516,18854156,10619015,8866474,12492861,9701805,12950914,14651647, 19450516 20566861 21235642 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:00, 18 January 2011
- Description: ATPase, centromere-like function involved in forespore chromosome partitioning / negative regulation of sporulation initiation
| Gene name | soj |
| Synonyms | spo0JA |
| Essential | no |
| Product | negative regulator of sporulation initiation |
| Function | forespore chromosome partitioning / negative regulation of sporulation initiation |
| MW, pI | 27 kDa, 4.903 |
| Gene length, protein length | 759 bp, 253 aa |
| Immediate neighbours | spo0J, yyaB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
DNA condensation/ segregation, sporulation/ other, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40970
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: regulates DNA replication initiation by either inhibiting or activating the DNA replication initiator protein DnaA PubMed
- Protein family: parA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P37522
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Tsutomu Katayama, Shogo Ozaki, Kenji Keyamura, Kazuyuki Fujimitsu
Regulation of the replication cycle: conserved and diverse regulatory systems for DnaA and oriC.
Nat Rev Microbiol: 2010, 8(3);163-70
[PubMed:20157337]
[WorldCat.org]
[DOI]
(I p)
Original publications
