Difference between revisions of "GsaB"
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=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3BS8 3BS8] ([[HemL]]) {{PubMed|20946885}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P71084 P71084] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P71084 P71084] | ||
| Line 119: | Line 119: | ||
=References= | =References= | ||
| − | + | <pubmed> 20946885</pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 14:17, 16 October 2010
- Description: glutamate-1-semialdehyde aminotransferase
| Gene name | gsaB |
| Synonyms | |
| Essential | no |
| Product | glutamate-1-semialdehyde aminotransferase |
| Function | biosynthesis of heme |
| MW, pI | 46 kDa, 5.644 |
| Gene length, protein length | 1287 bp, 429 aa |
| Immediate neighbours | ygaE, ygaF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU08710
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate (according to Swiss-Prot)
- Protein family: HemL subfamily (according to Swiss-Prot)
- Paralogous protein(s): HemL
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P71084
- KEGG entry: [2]
- E.C. number: 5.4.3.8
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Honghua Ge, Xinhuai Lv, Jun Fan, Yongxiang Gao, Maikun Teng, Liwen Niu
Crystal structure of glutamate-1-semialdehyde aminotransferase from Bacillus subtilis with bound pyridoxamine-5'-phosphate.
Biochem Biophys Res Commun: 2010, 402(2);356-60
[PubMed:20946885]
[WorldCat.org]
[DOI]
(I p)
