Difference between revisions of "CotB"
| Line 93: | Line 93: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|15699190,1691789}} | + | ** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]], [[GerR]]) {{PubMed|15699190,1691789,20435725}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[GerE]]: transcription activation {{PubMed|1518043}} | ** [[GerE]]: transcription activation {{PubMed|1518043}} | ||
| + | ** [[GerR]]: transcription activation {{PubMed|20435725}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 121: | ||
=References= | =References= | ||
| − | <pubmed> 19933362,1518043,2821284,14762006,1691789, 19933362 15699190</pubmed> | + | <pubmed> 19933362,1518043,2821284,14762006,1691789, 19933362 15699190 20435725</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 14:37, 4 May 2010
- Description: spore coat protein (outer)
| Gene name | cotB |
| Synonyms | |
| Essential | no |
| Product | spore coat protein (outer) |
| Function | resistance of the spore |
| MW, pI | 42 kDa, 9.831 |
| Gene length, protein length | 1140 bp, 380 aa |
| Immediate neighbours | ywrJ, cotH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU36050
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: outer spore coat, at the middle of the spore as a ring- or spiral-like structure PubMed
Database entries
- Structure:
- UniProt: P07789
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Giuseppina Cangiano, Antonio Mazzone, Loredana Baccigalupi, Rachele Isticato, Patrick Eichenberger, Maurilio De Felice, Ezio Ricca
Direct and indirect control of late sporulation genes by GerR of Bacillus subtilis.
J Bacteriol: 2010, 192(13);3406-13
[PubMed:20435725]
[WorldCat.org]
[DOI]
(I p)
Daisuke Imamura, Ritsuko Kuwana, Hiromu Takamatsu, Kazuhito Watabe
Localization of proteins to different layers and regions of Bacillus subtilis spore coats.
J Bacteriol: 2010, 192(2);518-24
[PubMed:19933362]
[WorldCat.org]
[DOI]
(I p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Rita Zilhão, Mónica Serrano, Rachele Isticato, Ezio Ricca, Charles P Moran, Adriano O Henriques
Interactions among CotB, CotG, and CotH during assembly of the Bacillus subtilis spore coat.
J Bacteriol: 2004, 186(4);1110-9
[PubMed:14762006]
[WorldCat.org]
[DOI]
(P p)
L Zheng, R Halberg, S Roels, H Ichikawa, L Kroos, R Losick
Sporulation regulatory protein GerE from Bacillus subtilis binds to and can activate or repress transcription from promoters for mother-cell-specific genes.
J Mol Biol: 1992, 226(4);1037-50
[PubMed:1518043]
[WorldCat.org]
[DOI]
(P p)
L B Zheng, R Losick
Cascade regulation of spore coat gene expression in Bacillus subtilis.
J Mol Biol: 1990, 212(4);645-60
[PubMed:1691789]
[WorldCat.org]
[DOI]
(P p)
W Donovan, L B Zheng, K Sandman, R Losick
Genes encoding spore coat polypeptides from Bacillus subtilis.
J Mol Biol: 1987, 196(1);1-10
[PubMed:2821284]
[WorldCat.org]
[DOI]
(P p)
