Difference between revisions of "Era"
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| − | * '''Description:''' GTP-binding protein<br/><br/> | + | * '''Description:''' GTP-binding protein, involved in the assembly of the 30S ribosomal subunit<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Product''' || GTP-binding protein | |style="background:#ABCDEF;" align="center"| '''Product''' || GTP-binding protein | ||
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || ribosome assembly |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 8.376 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 8.376 | ||
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=References= | =References= | ||
| − | + | ==Reviews== | |
| + | <pubmed> 19575570 </pubmed> | ||
| + | ==Original publications== | ||
<pubmed>12427945, 6330116 </pubmed> | <pubmed>12427945, 6330116 </pubmed> | ||
| − | |||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:29, 8 April 2010
- Description: GTP-binding protein, involved in the assembly of the 30S ribosomal subunit
| Gene name | era |
| Synonyms | bex, yqfH |
| Essential | yes PubMed |
| Product | GTP-binding protein |
| Function | ribosome assembly |
| MW, pI | 33 kDa, 8.376 |
| Gene length, protein length | 903 bp, 301 aa |
| Immediate neighbours | recO, cdd |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU25290
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Binds and hydrolyzes GTP and readily exchanges GDP for GTP
- Protein family: Era subfamily (according to Swiss-Prot) Era/Obg family
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P42182
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Naotake Ogasawara, Nara, Japan
Your additional remarks
References
Reviews
Robert A Britton
Role of GTPases in bacterial ribosome assembly.
Annu Rev Microbiol: 2009, 63;155-76
[PubMed:19575570]
[WorldCat.org]
[DOI]
(I p)
Original publications
Takuya Morimoto, Pek Chin Loh, Tomohiro Hirai, Kei Asai, Kazuo Kobayashi, Shigeki Moriya, Naotake Ogasawara
Six GTP-binding proteins of the Era/Obg family are essential for cell growth in Bacillus subtilis.
Microbiology (Reading): 2002, 148(Pt 11);3539-3552
[PubMed:12427945]
[WorldCat.org]
[DOI]
(P p)
P Z Wang, R H Doi
Overlapping promoters transcribed by bacillus subtilis sigma 55 and sigma 37 RNA polymerase holoenzymes during growth and stationary phases.
J Biol Chem: 1984, 259(13);8619-25
[PubMed:6330116]
[WorldCat.org]
(P p)
