Difference between revisions of "SpoIID"
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| − | * '''Description:''' required for complete dissolution of the asymmetric septum <br/><br/> | + | * '''Description:''' cell wall hydrolase (lytic transglycosylase), required for complete dissolution of the asymmetric septum <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || lytic transglycosylase |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || sporulation | |style="background:#ABCDEF;" align="center"|'''Function''' || sporulation | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' degrades the glycan strands of the peptidoglycan into disaccharide units {{PubMed|20159959}}, enhances [[SpoIIP]] activity {{PubMed|20159959}} |
* '''Protein family:''' | * '''Protein family:''' | ||
| Line 70: | Line 70: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''Interactions:''' [[SpoIID]]-[[SpoIIP]] {{PubMed|20159959}} |
| − | * '''Localization:''' | + | * '''Localization:''' cell membrane {{PubMed|20159959}} |
=== Database entries === | === Database entries === | ||
| Line 120: | Line 120: | ||
=References= | =References= | ||
| − | <pubmed>17376078,1946462,11886548,15752199 3011962 15699190, 15383836 </pubmed> | + | <pubmed>17376078,1946462,11886548,15752199 3011962 15699190, 15383836 20159959 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:07, 18 February 2010
- Description: cell wall hydrolase (lytic transglycosylase), required for complete dissolution of the asymmetric septum
| Gene name | spoIID |
| Synonyms | spoIIC |
| Essential | no |
| Product | lytic transglycosylase |
| Function | sporulation |
| MW, pI | 37 kDa, 9.764 |
| Gene length, protein length | 1029 bp, 343 aa |
| Immediate neighbours | ywmC, murAA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU36750
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: degrades the glycan strands of the peptidoglycan into disaccharide units PubMed, enhances SpoIIP activity PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane PubMed
Database entries
- Structure:
- UniProt: P07372
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: spoIID PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Cecile Morlot, Tsuyoshi Uehara, Kathleen A Marquis, Thomas G Bernhardt, David Z Rudner
A highly coordinated cell wall degradation machine governs spore morphogenesis in Bacillus subtilis.
Genes Dev: 2010, 24(4);411-22
[PubMed:20159959]
[WorldCat.org]
[DOI]
(I p)
Arnaud Chastanet, Richard Losick
Engulfment during sporulation in Bacillus subtilis is governed by a multi-protein complex containing tandemly acting autolysins.
Mol Microbiol: 2007, 64(1);139-52
[PubMed:17376078]
[WorldCat.org]
[DOI]
(P p)
Thierry Doan, Kathleen A Marquis, David Z Rudner
Subcellular localization of a sporulation membrane protein is achieved through a network of interactions along and across the septum.
Mol Microbiol: 2005, 55(6);1767-81
[PubMed:15752199]
[WorldCat.org]
[DOI]
(P p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836]
[WorldCat.org]
[DOI]
(I p)
P Eichenberger, P Fawcett, R Losick
A three-protein inhibitor of polar septation during sporulation in Bacillus subtilis.
Mol Microbiol: 2001, 42(5);1147-62
[PubMed:11886548]
[WorldCat.org]
[DOI]
(P p)
A Driks, R Losick
Compartmentalized expression of a gene under the control of sporulation transcription factor sigma E in Bacillus subtilis.
Proc Natl Acad Sci U S A: 1991, 88(22);9934-8
[PubMed:1946462]
[WorldCat.org]
[DOI]
(P p)
I Lopez-Diaz, S Clarke, J Mandelstam
spoIID operon of Bacillus subtilis: cloning and sequence.
J Gen Microbiol: 1986, 132(2);341-54
[PubMed:3011962]
[WorldCat.org]
[DOI]
(P p)
