Difference between revisions of "DltD"

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(References)
(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[dltA]]-[[dltB]]-[[dltC]]-[[dltD]]-[[dltE]]'' {{PubMed|7797557}}
  
* '''Operon:''' ''[[dltA]]-[[dltB]]-[[dltC]]-[[dltD]]-[[dltE]]''
+
* '''[[Sigma factor]]:''' [[SigD]] {{PubMed|7797557}}, [[SigX]] {{PubMed|14762009}}
 
 
* '''[[Sigma factor]]:''' [[SigD]], [[SigX]]
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** expression activated by glucose (4.0 fold) {{PubMed|12850135}}
+
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}  
+
** repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|7797557}}
** repressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7797557 PubMed]
 
  
* '''Regulatory mechanism:''' activated by [[YvrHb]]  [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed]
+
* '''Regulatory mechanism:'''  
** [[Spo0A]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/7797557 PubMed]
+
** activated by [[YvrHb]]  [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed]
 +
** [[Spo0A]]: transcription repression {{PubMed|7797557}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 10:18, 6 February 2010

  • Description: D-alanine transfer from undecaprenol-phosphate to the poly(glycerophosphate) chain

Gene name dltD
Synonyms ipa-2r
Essential no
Product D-alanine transfer from undecaprenol-phosphate
to the poly(glycerophosphate) chain
Function biosynthesis of teichoic acid
MW, pI 44 kDa, 9.858
Gene length, protein length 1176 bp, 392 aa
Immediate neighbours dltC, dltE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DltD context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU38530

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References