QoxD

• Description: cytochrome aa3 quinol oxidase (subunit IV)
  
  

Gene name	qoxD
Synonyms	ipa-40d
Essential	no
Product	cytochrome aa3 quinol oxidase (subunit IV)
Function	respiration
MW, pI	13 kDa, 5.942
Gene length, protein length	372 bp, 124 aa
Immediate neighbours	ywcE, qoxC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU38140

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Ubiquinol-8 + O₂ = Ubiquinone-8 + H₂O (according to Swiss-Prot)

• Protein family: cytochrome c oxidase bacterial subunit 4 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P34959

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: qoxD PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

N Azarkina, S Siletsky, V Borisov, C von Wachenfeldt, L Hederstedt, A A Konstantinov
A cytochrome bb'-type quinol oxidase in Bacillus subtilis strain 168.
J Biol Chem: 1999, 274(46);32810-7
[PubMed:10551842] [WorldCat.org] [DOI] (P p)