Difference between revisions of "FtsE"

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* '''Description:''' ABC transporter ([[FtsE]]-[[FtsX]]), required for proper activation of [[Spo0A]] and initiation of sporulation <br/><br/>
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* '''Description:''' [[ABC transporter]] (ATP-binding protein) ([[FtsE]]-[[FtsX]]), required for proper activation of [[Spo0A]] and initiation of sporulation <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || ABC transporter ([[FtsE]]-[[FtsX]])
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] (ATP-binding protein)  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || initiation of sporulation  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || initiation of sporulation  
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
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* '''Interactions:''' [[FtsE]]-[[FtsX]] {{PubMed|10092453}}
  
* '''Localization:'''
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* '''Localization:''' membrane associated (via [[FtsX]]) {{PubMed|10092453}}
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 19:51, 14 January 2010

Gene name ftsE
Synonyms
Essential no
Product ABC transporter (ATP-binding protein)
Function initiation of sporulation
MW, pI 25 kDa, 8.419
Gene length, protein length 684 bp, 228 aa
Immediate neighbours ftsX, cccB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
FtsE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU35260

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: membrane associated (via FtsX) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sharon Garti-Levi, Ronen Hazan, James Kain, Masaya Fujita, Sigal Ben-Yehuda
The FtsEX ABC transporter directs cellular differentiation in Bacillus subtilis.
Mol Microbiol: 2008, 69(4);1018-28
[PubMed:18573177] [WorldCat.org] [DOI] (I p)

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)