Difference between revisions of "YfkC"
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| − | * '''Description:''' mechanosensitive channel, similar to MscS <br/><br/> | + | * '''Description:''' [[transport proteins|mechanosensitive channel]], similar to MscS <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || mechanosensitive channel, similar to MscS | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[transport proteins|mechanosensitive channel]], similar to MscS |
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|style="background:#ABCDEF;" align="center"|'''Function''' || resistance to osmotic downshock | |style="background:#ABCDEF;" align="center"|'''Function''' || resistance to osmotic downshock | ||
Revision as of 08:55, 13 December 2009
- Description: mechanosensitive channel, similar to MscS
| Gene name | yfkC |
| Synonyms | |
| Essential | no |
| Product | mechanosensitive channel, similar to MscS |
| Function | resistance to osmotic downshock |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 32 kDa, 5.293 |
| Gene length, protein length | 840 bp, 280 aa |
| Immediate neighbours | yfkD, yfkB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU07940
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot), membrane PubMed
Database entries
- Structure:
- UniProt: O35043
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Erhard Bremer, University of Marburg, Germany homepage
Your additional remarks
References
Reviews
Christopher D Pivetti, Ming-Ren Yen, Samantha Miller, Wolfgang Busch, Yi-Hsiung Tseng, Ian R Booth, Milton H Saier
Two families of mechanosensitive channel proteins.
Microbiol Mol Biol Rev: 2003, 67(1);66-85, table of contents
[PubMed:12626684]
[WorldCat.org]
[DOI]
(P p)
Original Publications
Paul G Wahome, Ann E Cowan, Barbara Setlow, Peter Setlow
Levels and localization of mechanosensitive channel proteins in Bacillus subtilis.
Arch Microbiol: 2009, 191(5);403-14
[PubMed:19252899]
[WorldCat.org]
[DOI]
(I p)
Tamara Hoffmann, Clara Boiangiu, Susanne Moses, Erhard Bremer
Responses of Bacillus subtilis to hypotonic challenges: physiological contributions of mechanosensitive channels to cellular survival.
Appl Environ Microbiol: 2008, 74(8);2454-60
[PubMed:18310427]
[WorldCat.org]
[DOI]
(I p)
Paul G Wahome, Peter Setlow
Growth, osmotic downshock resistance and differentiation of Bacillus subtilis strains lacking mechanosensitive channels.
Arch Microbiol: 2008, 189(1);49-58
[PubMed:17665170]
[WorldCat.org]
[DOI]
(P p)
