Difference between revisions of "WalR"

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(Extended information on the protein)
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* '''Domains:'''  
 
* '''Domains:'''  
  
* '''Modification:'''
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* '''Modification:''' phosphorylated by [[WalK]] on an Asp residue
  
 
* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
  
* '''Effectors of protein activity:'''
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* '''Effectors of protein activity:''' phosphorylation likely affects DNA-binding activity
  
 
* '''Interactions:''' [[WalK]]-[[WalR]]
 
* '''Interactions:''' [[WalK]]-[[WalR]]

Revision as of 19:28, 30 November 2009

  • Description: two-component response regulator, controls cell wall metabolism

Gene name walR
Synonyms yycF
Essential yes PubMed
Product two-component response regulator
Function control of cell wall metabolism
MW, pI 27 kDa, 4.876
Gene length, protein length 705 bp, 235 aa
Immediate neighbours walK, trnY-Phe
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YycF context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU40410

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: OmpR family of two-component transcription regulators
  • Paralogous protein(s):

Genes controlled by WalR

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by WalK on an Asp residue
  • Cofactor(s):
  • Effectors of protein activity: phosphorylation likely affects DNA-binding activity
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 2D1V (DNA binding domain), 2ZWM (receiver domain)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed during vegetative growth, repressed during stationary phase PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications