Difference between revisions of "SpoIVCB"
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| − | * '''Description:''' sporulation-specific [[sigma factor]] (SigK) (N-terminal half), other part: ''[[spoIIIC]]'' | + | * '''Description:''' sporulation-specific [[sigma factor]] ([[SigK]]) (N-terminal half), other part: ''[[spoIIIC]]'' |
<br/><br/> | <br/><br/> | ||
| − | |||
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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| Line 96: | Line 95: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[sigK]]'' (composed of ''[[spoIVCB]]-[[spoIIIC]]'') {{PubMed|2536191}} |
| − | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190}} | + | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190,2841290}}, [[SigK]] {{PubMed|2841290}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed during sporulation in the mother cell ([[SigE]], [[SigK]], [[GerE]], [[SpoIIID]]) {{PubMed|15699190,2841290,10075739,7966271}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[GerE]]: transcription repression {{PubMed|10075739}} | ||
| + | ** [[SpoIIID]]: transcription activation {{PubMed|7966271}} | ||
| − | * '''Additional information:''' SigK is activated by processing of membrane-bound pro-SigK by the [[SpoIVFB]] metalloprotease {{PubMed|19805276}} | + | * '''Additional information:''' |
| + | ** SigK is activated by processing of membrane-bound pro-SigK by the [[SpoIVFB]] metalloprotease {{PubMed|19805276}} | ||
| + | ** ''spoIVCB'' and ''[[spoIIIC]]'' form a composite gene in the mother cell during sporulation by excising the intervening DNA sequence. | ||
=Biological materials = | =Biological materials = | ||
| Line 129: | Line 133: | ||
=References= | =References= | ||
| − | <pubmed>14526016,17720779,1900494,10438769,2492118,16385044,1691789,15383836,2536191,2163341,10931284,1577688,9852018,1942049,7814326,8550479,11959848,9501233,10400595,2115401,7592342,1518043,8226681,9078383,2514119,10611287,14523132, 19805276 </pubmed> | + | <pubmed>14526016,17720779,1900494,10438769,2492118,16385044,1691789,15383836,2536191,2163341,10931284,1577688,9852018,1942049,7814326,8550479,11959848,9501233,10400595,2115401,7592342,1518043,8226681,9078383,2514119,10611287,14523132, 19805276 10075739 7966271 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:57, 24 November 2009
- Description: sporulation-specific sigma factor (SigK) (N-terminal half), other part: spoIIIC
| Gene name | spoIVCB |
| Synonyms | cisB, sigK |
| Essential | no |
| Product | RNA polymerase sporulation-specific sigma factor (sigma-K) (N-terminal half) |
| Function | late mother cell-specific gene expression |
| MW, pI | 17 kDa, 8.208 |
| Gene length, protein length | 468 bp, 156 aa |
| Immediate neighbours | nucB, spoIVCA |
| Gene sequence (+200bp) | Protein sequence |
| Caution: The sequence for this gene in SubtiList contains errors | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU25760
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: sigma-70 factor family (according to Swiss-Prot)
- Paralogous protein(s):
Genes controlled by SigK
gerE, lipC, surC, yabG, yndL, yitB-yitA-yisZ
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P12254
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Arthur Aronson, Purdue University, West Lafayette, USA homepage
- Charles Moran, Emory University, NC, USA homepage
Your additional remarks
References
