Difference between revisions of "Nfo"
| Line 89: | Line 89: | ||
=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[nfo]]-[[yqfU]]'' {{PubMed|12486072}} | ||
| − | + | * '''[[Sigma factor]]:''' [[SigG]] {{PubMed|12486072}} | |
| − | |||
| − | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed late during sporulation in the forespore ([[SigG]]) {{PubMed|12486072}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| + | The gene ''[[yqfT]]'' is located between ''[[nfo]]'' and ''[[yqfU]]'', but is transcribed in the opposite direction. | ||
=Biological materials = | =Biological materials = | ||
| Line 119: | Line 120: | ||
=References= | =References= | ||
| − | |||
<pubmed>18203828,16237020,12949090,,12486072, </pubmed> | <pubmed>18203828,16237020,12949090,,12486072, </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:43, 22 November 2009
- Description: type IV apurinic/apyrimidinic endonuclease
| Gene name | nfo |
| Synonyms | yqfS |
| Essential | no |
| Product | type IV apurinic/apyrimidinic endonuclease |
| Function | repair of oxidative DNA damage in spores |
| MW, pI | 32 kDa, 5.371 |
| Gene length, protein length | 891 bp, 297 aa |
| Immediate neighbours | yqfT, cshB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU25130
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products (according to Swiss-Prot)
- Protein family: AP endonuclease 2 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P54476
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
The gene yqfT is located between nfo and yqfU, but is transcribed in the opposite direction.
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
