Difference between revisions of "FruR"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[fruR]]-[[fruK]]-[[fruA]]'' | + | * '''Operon:''' ''[[fruR]]-[[fruK]]-[[fruA]]'' (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS]) |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
** repressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ** repressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ||
| + | ** induced in the presence of fructose ([[FruR]]) (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS]) | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[Spo0A]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ** [[Spo0A]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ||
| + | ** [[FruR]]: transcription repression (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS]) | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 21:01, 5 October 2009
- Description: transcription repressor of the fru operon
| Gene name | fruR |
| Synonyms | |
| Essential | no |
| Product | transcription repressor |
| Function | regulation of fructose utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 27 kDa, 5.684 |
| Gene length, protein length | 753 bp, 251 aa |
| Immediate neighbours | yknZ, fruK |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU14380
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O31713
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647]
[WorldCat.org]
[DOI]
(P p)
Jonathan Reizer, Steffi Bachem, Aiala Reizer, Maryvonne Arnaud, Milton H Saier, Jörg Stülke
Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 12);3419-3429
[PubMed:10627040]
[WorldCat.org]
[DOI]
(P p)
