AdeC

• Description: adenine deaminase
  
  

Gene name	adeC
Synonyms	ade, yzaD
Essential	no
Product	adenine deaminase
Function	utilization of adenine as nitrogen source, purine salvage and interconversion
Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Purine catabolism
MW, pI	62 kDa, 4.724
Gene length, protein length	1731 bp, 577 aa
Immediate neighbours	ktrC, rnjA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU14520

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Adenine + H₂O = hypoxanthine + NH₃ (according to Swiss-Prot)

• Protein family: adenine deaminase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39761

• KEGG entry: [2]

• E.C. number: 3.5.4.2

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

P Nygaard, P Duckert, H H Saxild
Role of adenine deaminase in purine salvage and nitrogen metabolism and characterization of the ade gene in Bacillus subtilis.
J Bacteriol: 1996, 178(3);846-53
[PubMed:8550522] [WorldCat.org] [DOI] (P p)