ScoA

• Description: probable succinyl CoA:3-oxoacid CoA-transferase (subunit A)
  
  

Gene name	scoA
Synonyms	yxjD
Essential	no
Product	probable succinyl CoA:3-oxoacid CoA-transferase (subunit A)
Function	lipid metabolism
MW, pI	25 kDa, 6.613
Gene length, protein length	714 bp, 238 aa
Immediate neighbours	scoB, yxjC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU38990

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA (according to Swiss-Prot)

• Protein family: 3-oxoacid CoA-transferase subunit A family (according to Swiss-Prot)

• Paralogous protein(s): YodS

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3CDK

• Swiss prot entry: P42315

• KEGG entry: [3]

• E.C. number: 2.8.3.5

Expression and regulation

• Operon: yxjC-scoA-scoB-yxjF PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Lucy Stols, Min Zhou, William H Eschenfeldt, Cynthia Sanville Millard, James Abdullah, Frank R Collart, Youngchang Kim, Mark I Donnelly
New vectors for co-expression of proteins: structure of Bacillus subtilis ScoAB obtained by high-throughput protocols.
Protein Expr Purif: 2007, 53(2);396-403
[PubMed:17363272] [WorldCat.org] [DOI] (P p)

Juliane Ollinger, Kyung-Bok Song, Haike Antelmann, Michael Hecker, John D Helmann
Role of the Fur regulon in iron transport in Bacillus subtilis.
J Bacteriol: 2006, 188(10);3664-73
[PubMed:16672620] [WorldCat.org] [DOI] (P p)